ASPEN ch 14--PN overview Flashcards

1
Q

why crystalline a.a. better?

A

better utilized and lack preformed ammonia

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2
Q

3-in-1 also called ____ admixture

A

total nutrient

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3
Q

PN is hypertonic to body fluids and can result in _______ if admin inappropriately

A

venous thrombosis, suppurative thrombophlebitis, extravasation

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4
Q

osmolarity of PN formula primarily depend on these components:

A

dextrose (5mOsm/g), a.a. (10mOsm/g), electrolytes (1mOsm/g)

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5
Q

max osmolarity of PPN:

A

900mOsm

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6
Q

CPN often referred to as:

A

total parenteral nutr

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7
Q

why can handle greater osmolarity in CPN?

A

rate of blood flow in large vessels rapidly dilutes hypertonic formulation to that of body fluids, minimize risk of complications

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8
Q

PPN used up to ____ days

A

14

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9
Q

why PPN undesirable for pt on fluid restriction?

A

large fluid vols needed because can’t concentrate solution too much

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10
Q

why limit PPN?

A

tolerance limit, few suitable veins

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11
Q

for PPN must meet these 2 criteria:

A

good peripheral venous access and able tolerate large volumes of fluid

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12
Q

__ may be used to ^ energy density of PPN without increasing osmolarity, can improve vein tolerance of PPN:

A

ILE

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13
Q

use of ___ catheters recommended in pt needing PPN>6 days

A

midline (lower probability dislodge)

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14
Q

contraindications to PPN:

A

significant malnutrition, severe stress, large nutr/electrolyte needs, fluid restriction, prolonged PN need, renal/liver probs

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15
Q

____ concept is relevant to critically ill pt who don’t tolerate nutr (esp PN) well

A

permissive underfeeding

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16
Q

why permissive underfeed?

A

intended minimize complications of PN delivery by providing only 80% of est. energy requirements until condition improves

17
Q

___ feeding used in both EN and PN for obese to meet pro rqts but provide less nrg than estimated rqt

A

hypocaloric

18
Q

why use hypocaloric feed?

A

minimize metabolic complications of PB while improve N balance

19
Q

___ PN is approach designed to minimize energy deficit accumulated during period of no nutrition/undernutrition

A

supplemental

20
Q

indications for PN:

A

unable meet nutr rqts with EN, PPN up to 2 wks when pt can’t ingest/absorb PO or EN or when CPN not feasible, CPN necessary when >2wks and peripheral access limited/nutr needs large/fluid restrict

21
Q

use CPN when:

A

pt failed EN trial, EN contraindicated cuz of underlying condition, duration of starvation unknown and can’t tolerate EN/PO, clinical conditions

22
Q

PN should only be initiated if pt is ____ stable and can tolerate doses

A

hemodynamically

23
Q

when PN needed in pancreatitis, recommended that PN energy admin not exceed _____kcal/kg/d and glucose controlled

A

25-35

24
Q

why glutamine recommended in PN for pancreatitis?

A

minimize effect of being NPO on GI integrity

25
Q

how can surgery aggravate malnutrition?

A

stress produce proinflamm cytokines, ^ metabolic rate and catabolism, v LBM and aberrant glycemic control

26
Q

ratio of ___ to ___ may predict diminishing inflamm

A

prealbumin; CRP

27
Q

critical illness characterized by:

A

catabolic state result of SIRS to infectious/traumatic insult

28
Q

why gut failure common in critical ill?

A

preferential blood supply to vital organs

29
Q

why EN benefit in critically ill?

A

positive impact on immune barrier and decreasing permeability of GI tract to orgs (v inflamm); low risk of mesenteric ischemia when introducing EN

30
Q

critically ill pt needing PN fit this criteria:

A

malnourished at baseline, not reliably ingest EN for >7-10 days, adequately resuscitated from hemodynamic compromise (also if paralytic ileus, acute bleeding, bowel obstruction)

31
Q

most PN errors occur during ____ and ___ phase

A

transcription; admin

32
Q

how to decrease error?

A

multistep double check process, multidisciplinary teams

33
Q

PN should only be advanced when this criteria met:

A

stable BP, pulse, resp rates; normal electrolytes and glucose

34
Q

to prevent rebound hypoglycemia, PN should be ___ over 1-2 hours

A

tapered