Articular Cartilage Flashcards

1
Q

Elastic cartilage

A

External ear

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2
Q

Fibrous cartilage

A

Larynx, intervertebral discs

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3
Q

Hyaline cartilage

A

Joints

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4
Q

Thicker collagen, found in bone, tendon, ligament, and skin

A

Type I

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5
Q

Thinner fibril collagen (200nm) found in AC

A

Type II

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6
Q

AC provides ___

A

Low friction surface, shock absorption, distribute loads between opposing bones

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7
Q

T/F: AC has nerves and blood

A

False

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8
Q

Thickness of AC

A

1-6 mm

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9
Q

AC is lubricated with

A

Synovial fluid

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10
Q

Functional cells in AC

A

Chondrocytes

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11
Q

Backbone for PGs

A

Hyaluranic acid

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12
Q

Resist compression stresses and branch off of HA

A

Proteoglycans

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13
Q

Chondrocytes are found in larger numbers near

A

Articular surface and bone

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14
Q

Large protein-polysaccharide molecules with a protein core and glycosaminoglycans attached

A

Proteoglycans

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15
Q

Collagen ___ with PGs

A

Cross links

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16
Q

Near Articular surface, ___ are low and ___ is high

A

PGs; water

17
Q

Near subchondral bone, ___ is low and ___ are high

A

Water; PGs

18
Q

Collagen is strong under

A

Tension

19
Q

4 zones between articular surface and subchondral bone

A

Superficial tangential, middle, deep, (tide mark), calcified cartilage

20
Q

High water, low PG, fine collagen aligned parallel to surface, elongated chondrocytes parallel to surface

A

Superficial tangential zone

21
Q

Thicker collagen at 45 deg, rounded chondrocytes

A

Middle zone

22
Q

Thick collagen perpendicular to surface, high PG, low water, spherical chondrocytes in columns

A

Deep zone

23
Q

Separates AC from subchondral bone, tidemark

A

Calcified cartilage zone

24
Q

Breakdown of AC

A

Osteoarthritis

25
Q

As load increases, ___ decreases

A

Permeability

26
Q

AC has what 2 phases

A

Solid and fluid, elastic and viscous

27
Q

PGs help with ___ stiffness

A

Compressive

28
Q

How does AC react under impact load

A

Acts as a solid, PGs and collagen resist the load

29
Q

Types of tests for AC

A

Indentation, unconfined, confined