Aromatic Routes + Grignard Reagents Flashcards
What is the general formula of a Grignard Reagent?
RMgX
How do you make a Grignard reagent?
Reflux a halogenoalkane with magnesium in dry ether
How do you make a carboxylic acid from a Grignard Reagent?
1-Bubble CO2 through a Grignard Reagent in dry ether, then a dilute acid
How do you react Grignard Reagents to form alcohols?
React in dry ether, then add dilute acid
What happens when a Grignard Reagent reacts with methanal?
It forms a primary alcohol
What happens when a Grignard Reagent reacts with any aldehyde (except for methanal)?
It forms a secondary alcohol
What happens when a Grignard Reagent reacts with a ketone?
It forms a tertiary alcohol
What are the 4 compounds that benzene can react to form?
- Nitrobenzene
- Alkyl benzene
- Phenyketone
- Halobenzene
What route do you have to take to form phenylamine from benzene?
React benzene to from nitrobenzene, followed by reacting nitrobenzene to form pheylamine
How do you form halobenzene from benzene?
React with X2, a halogen carrier, and 20 degrees
What is the only thing phenol can react to form?
Tri bromophenol
How do you react phenol form tribromophenol?
React with bromine water (Br2) at room temp
How do you react benzene to form phenylketone?
React with an acyl chloride, AlCl3 catalyst and reflux
How do you form an alkyl benzene from benzene?
React with a halogenoalkane, AlCl3 catalyst and reflux
How do you form nitrobenzene?
Conc nitric and sulfuric acid under 55 degrees
