Approach to therapeutics in SA haemopoietic cases Flashcards
Indications for blood transfusion and clinical signs
Animal is severely anaemic
Tachycardia, Tachypnoeic
Non-immunologic transfusion reactions
Transmission of infectious disease
Hypocalcemia (Citrate in bag)
Circulatory overload
Bacteraemia
Categories of Immunologic transfusion reactions
Haemolytic
Non-Haemolytic
Consequences for Haemolytic immunologic transfusion (Acute)
Acute intravascular haemolysis- Haemoglobinuria
Activation of haemostatic system (DIC)
Hypotension
Death
Consequences for Haemolytic immunologic transfusion (Delayed/2-21 days)
Extravascular haemolysis
Negates the potential benefit of the transfusion
What is the name of blood group for canine that is most relevant to blood transfusion
DEA 1.1
How does blood groups differ from dogs and cats
DEA vs AB bloodgroup system
Cats have naturally occuring allo-antibodies
Incompatible transfusion WILL result in haemolytic transfusion reaction even if its the first time the cat is transfused
Consequence of Type A cat receiving Type B blood
Mild/Moderate transfusion reaction that negates benefits of blood transfusion
Consequence of Type B cat receiving Type A blood
Severe transfusion reaction
Crossmatching
Used to detect antibodies to RBC
What is the equation of blood transfusion volume for DOGS
90xBodyweightx(Desired PCV-Recipient PCV) / Donor PCV
What is the equation of blood transfusion volume for CATS
60xBodyweightx(Desired PCV-Recipient PCV) / Donor PCV
Volume of blood needed for coagulopathies
10-20mls/kg of plasma
How quickly should you administer blood transfusion
Start at 0.5-2mls/kg/hr for 30 mins
Hypovolemic: 20mls/kg/hr
Normovolaemic: 5-10mls/kg/hr
Cardiac/Renal disease: 2mls/kg/hr
