Apoptosis and Necrosis Flashcards
________: Programmed Cell death
Apoptosis
______ and ________ are the two general forms of cell death.
Apoptosis and Necrosis
_________ is programmed, whereas ______ is more incidental and can occur due to unintended damage.
Apoptosis
Necrosis
What are 2 times that one might expect to see apoptosis occur?
1) During Embryonic Development
2) During Immune System Development
During embryonic development or immune system development, one might expect to see __________ occur during the process.
Apoptosis
Necrosis is \_\_\_\_\_\_\_\_\_\_\_\_ pathological. A) Rarely B) Sometimes C) Always D) Never
C) ALWAYS
This apoptotic pathway is initiated by interior signaling due to irreparable, irreversible DNA damage.
Intrinsic apoptotic pathway
This apoptotic pathway is initiated by exterior signals due to indications of damage or infection.
Extrinsic Apoptotic Pathway
What is cell ‘blebbing’?
When a cell disintegrates into small vesicles and are taken up by phagocytosis.
________ destroy proteins and other molecules within the cell during apoptosis.
Caspases
This form of apoptosis is caspase-independent.
AIF-Apoptosis-Inducing Factor
This form of apoptosis will invade the nucleus, initiate chromatin development, and clip the ‘beads on a string’ and then bleb out.
AIF-Apoptosis
Increasing ______ ________ drives the pH down denaturing proteins leading to the collapse of the cell membrane and causing necrosis.
Lactic acid
Lysosomal hydrolytic enzymes will inappropriately clip up stuff after necrosis and you will see an __________ response. This type of response can lead to the development of _________.
Inflammatory
Cancer (because inflamed cells are less likely to initiate apoptosis)
