apgar score lactation menopause Flashcards

1
Q

Apgar score - use

A

assessment of newborn vital sign following labor vua a 10 point scale evaluated at 1 minute and 5 minutes

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2
Q

Apgar score is based on

A
Appearance
Pulse
Grimace 
Activity 
Respiration
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3
Q

Apgar score - score for appearance

A

pink –> 2
extremities blue –> 1
pale or blue –> 0

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4
Q

Apgar score - score for Pulse

A

more than 100 –> 2
less than 100 –> 1
no pulse –> 0

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5
Q

Apgar score - score for Grimace

A

cries and pulls away –> 2
Grimaces or weak cry –> 1
no response to stimulation –> 0

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6
Q

Apgar score - score for Activity

A

active movement –> 2
arms, legs flexed –> 1
no movement –> 0

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7
Q

Apgar score - score for Respiration

A

strong cry –> 2
slow irregular –> 1
no breathing –> 0

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8
Q

Apgar score - management/evaluation/meaning

A

if less than 7 –> further evaluation

if remains low at later time points –> increased risk to develop long-term neurological damage

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9
Q

Low birth weight definition

A

less than 2500 g

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10
Q

mechanism of low birth weight

A

preamaturity or intrauterine growth restriction (IUGR)

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11
Q

2 causes of low birth weight

A
  1. cocaine

2. smoking

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12
Q

Leading cause of low birth weight in developed countries

A

smoking

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13
Q

Complications of low birth weight

A
  1. high risk of sudden infant death (SIDS)
  2. impaired thermoregulation
  3. impaired immune function
  4. hypoglycemia
  5. polycythemia
  6. impaired neurocognitive/emotional development
  7. infections
  8. respiratory distress syndrome
  9. necrotizing enetrocolitis
  10. intraventricular haemorrhage
  11. persistent fetal circulation
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14
Q

breast/lactation during pregnancy

A
  • Estrogens + progesterone stimulate growth and development of breasts during pregnancy
  • prolactin levels increase during prengncy because estrogen stimulate anterior pituitary
  • lactation does not occut because estrogne and progesterone blocks prolactin’s action on the breast
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15
Q

lactation after the labor

A

the low levels of pregnancy and estrogen disinhibit lactation

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16
Q

hormones of lactation - regulation of production and action

A

suckling is required to maintain milk production, since high nerve stimulation –> increased oxytokin+prolactin:

a. prolactin –> induce+maintains lactation and decreases reproductive function
b. oxytokin –> assists milk letdown (also uterine contraction)

17
Q

prolactin inhibits reproductive function via

A

inhibition of GnRH

18
Q

breast milk is the ideal nutrition for infants …(age)

A

younger than 6 months

19
Q

breast milk contains

A
  1. maternal immunoglobulins conferring passive immunity, mostly IgA)
  2. macrophages
  3. lymphocytes
20
Q

breast milk effects on infants

A
  1. reduce infant infections

2. associated with low risk for child develop 3. asthma, 4. allergies, 5. DM, 6. obesity

21
Q

Exclusively breastfed infants require ….

A

vitamin D supplementation

22
Q

breastfeeding effects on mother

A
  1. decreases maternal risk of breast and ovarian cancer

2. facilitates mother-child bonding

23
Q

Menopause is diagnosed by (clinically)

A

amenorrhea for 12 months

24
Q

amenorrhea

A

an abnormal absence of menstruation.

25
Q

average age of menopause

A

51 (earlier in smokers)

26
Q

menopause associated hirsutism - mechanism

A

decreased estrogen production due to age-linked decline in number of ovarian follicles

27
Q

menopause usually preceded by

A

4-5 years of abnormal menstrual cycles

28
Q

source of estrogen after menopause

A

peripheral conversion of androgens –> estrone

29
Q

menopause - mechanism

A

Ovarian estrogen secretion declines rapidly, whereas ovarian androgen production continues for a few years after menopause. Androgen production after menopause is gonadotropin dependent and, when excessive, can lead to hirsutism

30
Q

hormonal changes in menopause

A
  1. low estrogen
  2. high LH (no surge)
  3. VERY high FSH
  4. high GNRH
  5. high androgens
31
Q

specific lab finding for menopause (and mechanism)

A

very high FSH (loss of negative feedback on FSH due to low estrogen)

32
Q

menopause - presentation

A
  1. hot flashes 2. atrophy of vagina 3. Osteoporosis
  2. Coronary artery disease 5. Sleep disturbances
  3. Hirsuitism
33
Q

Menopause before 40 suggests

A

1ry ovarian insuficiency (premature ovarian failure)