anatomy Flashcards
gonadal - venous drainage
Left ovary/testis –> left gonadal vein –> left renal vein
–> IVC
Right ovary/testes –> right gonadal vein –> IVC
left vs right gonadal vein
Left –> left renal –> IVC
right –> IVC
gonadal vein - female vs male
female –> ovarian vein
male –> testicular vein (or spermatic vein)
clinical significance of speramatic vein
Because left spermatic vein enters the left renal vein at 90 degrees, flow flow is less laminar on left than right
–> more pressure on left vein –> varicocelle more common in left
varicocelle is more common in left or right side
left
Cervical, hilar, Mediastinal, Axillary lymph node cluster drains … (area)
cervical –> head and neck
hilar –> lungs
mediastinal –> Trachea and esophagus
axiallary –> Upper limb, breast, skin above umbilicus
Celiac lymph node cluster drains … (area)
liver, stomach, spleen, pancreas, upper duodenum
Superior mesenteric lymph node cluster drains … (area)
lower duodenum, jejunum, ilieum, colon to splenic fructure
Inferior mesenteric lymph node cluster drains … (area)
colon from splenic flexure to upper rectum
Para-aortic lymph node cluster drains … (area)
- Testes
- ovaries
- kidneys
- uterus
internal iliac nodes drain
- lower rectum to anal canal (above the line)
- cervix
- corpus carvenosum
- vagina (middle third)
- prostate
superficial inguinal drain
- anal canal (below the line)
- skin below umbilicus (except popliteal area)
- scrotum
- vulva
- vagina (lower third)
deep inguinal nodes
glans penis
external iliac nodes
- body of uterus
- cervix (and upper third of vagina)
- superior bladder
cervix lymph drainage
external and internal iliac nodes
uterus lymph drainage
Para-aortic external iliac (body)
lymph drainage - uterus, cervix, vagina
para-aortic uterus –> uterus
external iliac –> body of uterus, cervix, upper third vagina
internal iliac –> cervix, middle third vagina
superficial inguinal –> lower third vagina
Lymphatic drainage of the vagina is generally to the
external iliac nodes (upper third of the vagina), internal iliac nodes (middle third), and the superficial inguinal nodes (lower third).
Fenale reproductive system - ligaments
- infundibulopelvic ligament (suspensory ligament of the ovary)
- Cardinal ligament
- Round ligament of uterus
- Broad ligament
- Ovarian ligament
- uterosacral
Fenale reproductive system - ligaments an what they connect
- infundibulopelvic (suspensory ligament of the ovary) –> ovaries to lateral pelvic
- Cardinal –> cervix to side wall of pelvis
- Round ligament of uterus –> uterine fundus to labia major
- Broad –> uterus, fallopianm tuves and ovaries to pelvic side wall
- Ovarian –> madian pole of ovary to lateral uterus
- uterosacral –> uterus to the anterior aspect of the sacrum
infundibulopelvic ligament is AKA
suspensory ligament of the ovary
infundibulopelvic (suspensory ligament of the ovary) connects
ovaries to lateral pelvic
infundibulopelvic (suspensory ligament of the ovary) contains
ovarian vessels
cardinal ligament connects
cervix to side wall of pelvis
cardinal ligament contains
uterine vessels
Round ligament of the uterus connects
uterine fundus to labia majora
Round ligament of the uterus contains
nothing
Broad ligament connects
uterine, fallopian tubes and ovaries to pelvic side wall
Broad ligament contains
ovaries, fallopian tuves, round ligaments of uterus
uterosacral ligament connects
uterus to the anterior aspect of the sacrum
ovarian ligament connects
medial pole of ovary to lateral uterus
ovarian ligament contains
nothing
Derivatives of gubernaculum in females
- ovarian ligament
2. round ligament of the uterus
course of round ligmament of the uterus
travels along inguinal canal, in the broad ligament, above the artery of Sampson
Sampson artery
- runs under the round ligament of uterus.
- is anastomosis of the uterine artery and ovarian artery
Broad ligament - structure
Fold of peritoneum that comprises the
- mesosalpinx
- mesometrium
- mesovarium (suspends the ovaries)
ureter course in females
retroperotoneally, close to gonadal vessels (risk at injury during ligation of ovarian vessels) and under uterine artery)
(risk at injury during ligation of ovarian or uterine vessels)
an operation with uterine vessels ligation
hysterectomy
clinical correlation of infundibulopelvic ligament
- very close to ureter –> risk of injury during ligation
2. ligate vessels during oophorectomy to avoid bleeding
vagina histology
stratified squamous epithelium, nonkeratinized
ectocervix histology
stratified squamous epithelium, nonkeratinized
transformation zone (female reproductive) histology
Squamocolumnar junction (ectocervic-endocervix)
endocervix histology
simple columnar epithelium
uterus histology
simple columnar epithelium with long tubular glands in proliferative phase
coiled glands in secretory phase
fallopian tube histology
simple columnar epithelium, ciliated
ovary, outer surface histology
simple cuboidal epithelium (germinal epithelium covering surface of ovary
uterus walls
inside –> endometrium
middle –> myometrium
outside –> Perimetrium
perimetrium?
Serous layer of visceral peritonium. It covers the outer surface of the uterus
ovarian artery arises from
abdominal aorta (above L2)
uterine artery arises from
anterior division of the internal iliac artery
ovarian and uterine anastomosis
Sampson artery
portions of cervix
- endocervix
- transitional zone
- ectocervix
cervical os?
- external os: the external opening into the vagina
2. internal os: theinternal opening into the endometrial cavity
Vaginal fornix (fornices of the vagina)
superior portions of the vagina, extending into the recesses created by the vaginal portion of cervix
- posterior - behind the cervix (largest)
- anterior
- twο lateral
infundibulopelic - course according to Fallopian tube
it goes under
regions of Fallopian tube (from inner to outer)
uterine –> isthmus –> ampula –> infundibulum –> Fimbriae (ostium)
parts of male urethra (and direction)
(AFTER bladder and bladder neck) preprostatic urethra –> prostatic –> membranous urethra (through pelvic floor) –> spongy (penile) within the bulb and corpus sponsgiosum
spongy (penile urethra) is sometimes further divided to
bulbar and penile urethra
suspect urethreal injury in males if
blood seen at urethral meatus
male urethral injury - division according to location
posterior urethra - membranous
anterior urethra - bulbar and penile urethra
posterior urethra (membranous) trauma
prone to injury from pelvic fracture –> injury can cause urine to leak into retropubic space
Retropubic space is the
extraperitoneal space between the pubic symphysis and urinary bladder
anterior urethra bulbar and penile trauma
at risk of damage due to perineal straddle injury –> urine leak beneath deep fascia of Buck –> if fascia is torn, urine escapes into superficial perineal space
straddle injury
perineal trauma
Buck’s fascia?
or fascia of the penis –> is a layer of deep fascia covering the three erectile bodies of the penis
Pathway of sperm during ejaculation
mnemonic: SEVEN UP
Seminiferous tubules –> Epidedidymis –> Vas deferens
–> Ejaculation ducts –> urethra –> penis
histology of testis and epdidemis
seminiferous tubules (Leyding cells between them, separated by septa) and covered by tunica albuginea –> concentrate in Rete testis –> head of epididymis (efferent ductule) –> tale of epididymis –> vas deferens
Prepuce?
- Clitoral hood, skin surrounding and protecting the head of the clitoris
- Foreskin, skin surrounding and protecting the head of the penis in humans
Corpus cavernosum vs corpus spongiosum
according to anatomy
corpus spongiosum –> mass of spongy tissue surrounding the male urethra within the penis (ventral)
Corpus cavernosum –> 2 sponge like regions on erectile tissue of penis (dorsal)
erection is control by
parasympathetic nervous system (pelvic nerve)
erection mechanism
NO –> increased cGMP –> SMCs relaxation –> vasodilation -> proerectile
norepinephrine in erection
norepinephrine increases Ca2+ concentration in in SMCs –> vasoconstriction –> antierectile
emission definition/controled by
phase when sperm moves from testes upto prostatic urethra. It is controlled by sympathetic nervous systme (hypogastric nerve)
ejaculation definition/controled by
phase when sperm moves from prostatic urethra to the outside. It is controlled by visceral and somatic nerves (The pudendal nerve)
emission vs ejaculation according to definition
emission –> phase when sperm moves from testes upto prostatic urethra
ejaculation –> phase when sperm moves from prostatic urethra to the outside
Seminiferous tubules - cells
- spermatogonia (germ cells)
- sertoli cells (non germ cells)
- Leyding cells (endocrine cells)
Seminiferous tubules - cells/location
- spermatogonia (germ cells) –> line seminiferous tubules
- sertoli cells (non germ cells) –> line seminiferous tubules
- Leyding cells (endocrine cells) –> intersitium (outside the tubule)
spermatogonia (germ cells) - function
maintain germ pool and produce primary spermatocytes
spermatogonia to sprmatozoon (only the cells)
spermatogonium –> sprmatocytes (1ry and 2ry) –> speramtides –> spermatozoon (spermatozoon in the lumen of seminiferous tubule) (SPERMATOGENESIS)
sertoli cells (non-germ cells) - location
line of seminiferous tubules
sertoli cells (non-germ cells) - action
- secrete inhibin B (inhibits FSH)
- secrete androgen-binding protein (maintain local levels of testosterone –> stimulate spermatogenesis)
- produce MIF (suppress development of paramesonephric ducts)
- form the blood-testis barrier –> isolate gametes from autoimmune attack
- sapport and nourish developing spermatozoa
- Regulate spermatogenesis
- convert testosterone and androstenedione to estrogens via aromatase
sertoli cells (non-germ cells) are sensitive to
temperature
sertoli cells (non-germ cells) are sensitive to … (explain)
temperature:
increased Q –> low sperm production and low inhibin B
situations that increases temperature in seminiferous tubules
- Varicocele
2. crytorchidism
Blood-testis barrier - structure and function
structure: tight junction between Sertoli cells
function: a. isolates gametes from autoimmune attack
b. prevent cytotoxic agents
sertoli cells - homolog of female
granulosa cells
Leyding cells (endocrine cells) - function
secrete testosterone in the presence of LH
Leyding cells (endocrine cells) vs temperature
testosterone production unaffected by temperature
Leyding cells - area
interstitium of Seminiferous tubules
Leyding cells - homolg of female
theca interna cells
which ligaments of the female reproductive system contain nothing
the derivatives of gubernaculum
- Round ligaments of the uterus
- ovarian ligament
which ligaments of the female reproductive system contain tha major vessels of the area
- infundibulopelvic ligament –> ovarian vesses
2. cardinal vessels –> uterine vessels
Female reproductive epithelial histology - MC area of cervical cancer
transformation zone
breast - suspensory ligaments - aka and course
aka: Cooper
course: separate the the lobes + attach the skin
breast - arterial supply
branches of:
- internal thoracic (sublavian)
- lateral thoracic (axillary)
- anterior + posterior intercoastal
breast - lymph nodes
- most: axillary
2. part of medial quadrants: parasternal
radial mastectomy?
breast is removed along with pectoralis major and minor, axillary nodes and vessels, and tributaries of axillary vein
SA node location
in the sinus venarum of the RA near the entrance of the SVC
AV node location
interatrial septum - RA near TV and the orifice of coronary sinus
inf epigastric artery - course
branch of ext iliac immediately proximal to inguinal ligament –> supply to lower anterior abdominal wall as it rans superiorlu + and medially up to abdomen
superior gluteal artery - course
the continuation of internal iliac artery –> post/inf to supply gluterus and a portion of hip
obturator artery - course
branch of internal iliac –> inf to supply pelvic organs
ext iliac artery branches
- inf epigastric
2. deep circumflex iliac
great saphenous course
medial side of food –> anterior to medial malleolus –> medial aspect of leg + tight –> drains into demoral in the femoral tirangle (inferolateral to pupitubercle)
small saphenous vein course
lateral foot –> posteriorly –> into popliteal vein
perineal body?
central tendon of the perineum –> lies in the midline between urogenital + anal triangle
the following structures are anchored to it:
1. bulbospongiosus muscle
2. external anal sphincter
3. superficial + deep transverse perinal muscle
4. fibers from external urethral sphincter, levator ani + muscular coat of rectum
hip bone is consists by
3 bones: ilium, ischium, pubis
pelvis diaphragm weakness –>
prolapse of uteros, bladder or rectum into vagina
vesicouterine vs rectovesical pouch
females –> peritoneum onto anterior aspect of uterus (between uterus + bladder) –> vesicouterine pouch
males –> peritoneum onto anterior aspect of the rectum (between rectum + uterus –> rectovesical pouch
position of uterus
50% –> anterverted
25% retroverted
25% midverted
due to uterosacral ligament –> loss of the ligament –> prolapse into vagina
fructose rich compoment of sperm, and area
area of Bulbourethral gland of Cowper
seminal vesicle (posteriolateral of bladder) seminal vesicle in ductus deferans (behind bladder) --> ejaculation duct cowper: junction between membranous + boublous urethra
The recto-uterine pouch( pouch of Douglas)?
extension of the peritoneal cavity between the rectum and the posterior wall of the uterus in the female human body
epistomy - definition + types
it is an incision of the posterior wall of the vagina during labor:
- medline: extend posteriorly in the midline throught perineal body (vertical)
- mediolateral: extend througth the bulbospongiosus + transcerus perineus muscle (less risk of damage fibers of external anal sphincter)
urogenital dipahragm is transverse by / contains
urethra in both sexes + by vagina
contains deep transversus perineus muscles + sphincter urethrae (external sphincter)
branches of internal iliac artery
- pelvic visceral branches: umbilical ar, uterine ar, ductus deferens, vaginal art, inferior vesical ar, middle rectal ar
- perineal branches: internal pubendal –> inf rectal, perineal branch, artery to bulb, deep ar of penis, dorsal ar of penis
- pelvic wall branches –> iliolumbar, lateral sacral
- lower limb branches –> superior glut, inf glut, oburator ar
pudendal nerve - branches
3 main branches –> inf rectal, perineal nerve, dorsal nerve of penis + clitoris
unresponsive to medical management postpartum hemorrhage –>
bilateral ligation of the internal iliax artery (aka as hypogasric artery)
the uterus has collateral blood flow (from ovarian art) –> sufficient to maintain uterine function
internal pupendal artery course
branch of anterior trunck of internal iliac –> runs througth the schiatic foramina –> supply the perineum
main risk of ovarian torsion
large ovarian mass
pampiform plexus
receive venous blood from testis, epididymis, ductus deferans –> drains into testicular veins
pelvic innervation
- pudendal (S2-4) –> sensory: perineum, motor: urethral+anal sphincter
- Lateral femoral cutaneous (L2-3) –> sensroy: anter + lateral tight (injury during hyperflexion of the thighs for pelvic surgery or vaginal delivery
- inferior gluteal
- Genitofemoral (L1-2) –> sensory: scrotum/labia majora, medial thigh (anterior to psoas, injury during laparotomy), motor to parts of genitalia (eg. cremasteric reflex)
- Obturator
- Iliohypogastric (T12-L1) –> sensory hypogastric (injury due to Pfnannestiel skin incisions, like cesarean, appendidectomy), motor to anterolateral abdom walls
- ilioinguinal (L1) –> sensory from skin of the upper + medial thigh, the root of penis + upper scrotal, labia major
pupendal nerve - landamark
ischial spine + sacrospinous ligament
(other important structures: internal pupendal ar + inf gluteal ar - run medial to nerve
prostatic plexus - lies … / origin /
- lies within the fascia of prostate
- origin: inferior hypogastric plexus
- gives rise to lesser + greater carvenous nerves
risk for injury in prostatectomy –> erectile dysfunctin
fibrinoids of uterus may located
- serosal surface (subserosal) –> IRREGULAR ENLARGED UTERUS –> bulk symptoms (eg. constipation)
- within uteral wall (intramural) –> reproductive difficulties
- below endometrium (SUBMUCOSAL) –> reproductive difficulties, bleeding
imperforate hymen
by incomplete degeneration of the central portion of fibrous tissue band connecting the wall vagina –> priamary amenorrhea, normal secondary sexal, cyclic pelvic pain due to accumulation of blood in vagina + uterus (hematocopos), palbable mass anterior to rectum, difficulties in defecation
endometriosis in pouch of douglas
painful defecation, dyspareunia, plpable nodularity on rectpvaginal examination
main target of kegel exercise
levator ani:
- iliococcygeus
- pubococcygeus
- puborectalis
levator ani injury –>
- urethral hypermobility
2. pelvic organ prolapse
gonadal arteries course
right travels in front of IVC + behind ileum + left ar behind left colic + sigmoid art + iliac colon –> cross anteror the ureter –> paraller the external iliac vessels –> inguinal canal –> testes
prostate location
types of obstruction in BPH
between pubic symphisis + + anal canal
- static obstriction (androgen-mediated)
- dynamic obstriction (α adrenoreceptor mediated)
penile venous outflow anomalies
eg. leakflow of vein –> erectile dysfunction
vasectomy?
remove of ductures deferens (vas deferens) –> birth control
lymphatic system of lower extremities
- superficial lymphatic vessels (follow venous system)
- deep lymphatic vessels (follow arterial system)
the superficial lymphatic system is also divided to medial + lateral
medial bypass the popliteal nodes (like saphenus) –> inguinal area
lateral do not bypass –> popliteal AND inguinal area
bladder lymph drainage
superior: external iliac
inferior: internal iliac
arcuate line?
horizontal line below the umbilicus that demarcates the lower limit of the posterior rectus sheath. Above that, the rectus abdominis is sourounded by anterior + posterior sheath. Below only by anterior sheath
inscision in cesarea delivery
- midline vertical sepration of the rectus abdominis muscle
- when additionally space necessary –> horizontal transection of the rectus abdominis –> risk for inferior epigastric arteries