AP02 - Cartilage and bones Flashcards
What are the three types of cartilage?
- Hyaline
- Elastic
- Fibrous
What are the main cell types in cartilage?
Chondrocytes
Where is the location of collagen fibre type 1?
- Bone
- Skin
- Dentin
- Cornea
- BV
- Fibrocartilage
- Tendon
Where is the location of collagen fibre type 2?
Cartilaginous tissues
Where is the location of collagen fibre type 3?
- Skin
- Ligaments
- BV
- Internal organs
Where is the location of collagen fibre type 4?
- B. memb in various tissues
Where is the location of collagen fibre type 5?
- BV wall
- Synovium
- Corneal stoma
- Tendon
- Lung
- Bone
- Cartilage
- Skeletal muscle
Describe the structure/ appearance of hyaline cartilage?
- Matrix contains moderate amount of collagen fibres
- Glassy appearance in living tissue
- Highly hydrated nature of the ground substance which consists of 3 types of GLYCOSAMINOGLYCANS
- Almost friction free surface (low coefficient of friction)
- Shock absorber
Describe the structure/ appearance of elastic cartilage?
- Matrix contains collagen fibres along with a large number of elastic fibres
- Elastic fibre netwrorks and collagen type II fibres
- Principal protein is elastin
- Springy and yellow
Describe the structure/ appearance of fibrous cartilage?
- Matrix contains limited number of cells and ground substance amidst a substantial amount of collagen fibres
- Tough and v strong
- Contains cartilage ground substance and chondrocytes
What are the three types of glycosaminoglycans found in hyaline cartilage?
- Hyaluronic acid
- Chondroitin sulphate
- Keratin sulphate
Where can hyaline cartilage be found?
- Embryonic skeleton
- Costal cartilages
- Cartilage of the nose, trachea, lining of the ends of some bones and larynx
Where can elastic cartilage be found?
Found in the internal support of the external ear and epiglottis
Where can fibrous cartilage (fibrocartilage) be found?
Found in the intervertebral discs and pubic symphysis
What is cartilage?
- Avascular form of CT
- Consists of extracellular fibres embedded in a matrix that contains cells localised in small cavities
- Amount and kind of extracellular fibres in the matrix varies depending on type of cartilage
- Nourished by diffusion
- No BV/ lymphatics or nerves