Anxiotlytics Flashcards
Benzodiazapines
Most common:
clonazepam
diazepam
alprazolam
lorazepam
Oxazepam
Chlordiazepoxide
Clorazepate
Buspirone
action:
5-HT1A agonist
D2 agonist
D2 antagonist
desired outcome:
Relieves anxiety
S/E
Nausea, headache, dizziness
Restlessness
interactions of Anxiiolytics
■Increased effects of antianxiety agents can occur when they are taken concomitantly with alcohol, barbiturates, narcotics, antipsychotics, antidepressants, antihistamines, neuromuscular blocking agents, cimetidine, or disulfiram.
■The FDA (2016a) added a boxed warning (its strongest warning) related to the serious risks and possible death associated with combining benzodiazepines with opioid pain or cough medicines.
■Increased effects can also occur with herbal depressants (e.g., kava, valerian, lemon verbena, L-tryptophan, melatonin, and chamomile).
■Decreased effects can be noted with cigarette smoking and caffeine consumption.
Nursing interventions for anxiolytics (Benzo’s)
*Do no stop abruptly- must taper off
*may cause drowsiness: do not operate heave machinery/drive
*No not mix with alcohol and other CNS depressants including:
antihistamines, cimetidine, antidepressants, neuromuscular blocking agents, or disulfiram while taking these drugs.
Black box warning for Benzo’s
do not mix with opioid medications or cough meds
blood dyscrasias
assess for sore throat, fever, bruising or unusual bleeding