Antivirals and Vaccines Flashcards
1
Q
What are the different sites of action of antivirals (6)
A
Fusion - HIV fusion inhibitors
reverse transcription - nucleoside analogues (NRTI)
Integration - Antiretroviral activity via Integrase inhibitors (INI):
Replication - Nucleoside analogues
Budding - Influenza virus neuraminidase inhibitors
Maturation - Protease inhibitors
2
Q
What is the basis of ART (3)
A
- Highly active antiretroviral therapy
- Combination of three drugs
- Prevents antiviral resistance
3
Q
What are the different types of vaccines (5)
A
Live attenuated vaccines
Inactivated/killed vaccines
Subunit vaccines
Recombinant vaccines
DNA/RNA vaccines
4
Q
What are the measures of control for disease prevention (7)
A
- Hygiene
- Barrier methods of contraception
- Needle exchange services
- Isolation
- PPE
- Vector control
- Quarantine
