Antimicrobial Therapy and infection control Flashcards

1
Q

Do Glycopeptides treat Gram ve- or Gram Ve + or both

A

positive

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2
Q

Do quinolones treat Gram ve- or Gram Ve + or both

A

both

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3
Q

Do tetracyclines treat Gram ve- or Gram Ve + or both

A

both

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4
Q

Do macrolides treat Gram ve- or Gram Ve + or both

A

mostly positive
some negative

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5
Q

Do aminoglycosides treat Gram ve- or Gram Ve + or both

A

negative

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6
Q

Do penicillins treat Gram ve- or Gram Ve + or both

A

positive and negative cocci

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7
Q

Do cephalosporins treat Gram ve- or Gram Ve + or both

A

both

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8
Q

Do carbapenems treat Gram ve- or Gram Ve + or both

A

both

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9
Q

Do lincosamides treat Gram ve- or Gram Ve + or both

A

positive

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10
Q

Do sulfonamides treat Gram ve- or Gram Ve + or both

A

both

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11
Q

Does isoniazid treat Gram ve- or Gram Ve + or both

A

both

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12
Q

What are the current challenges with antimicrobial resistance (4)

A

Resistance plasmids can bring about:
1. Antibiotic degrading enzyme
2. Antibiotic-altering enzyme
3. antibiotic efflux pump - spits antibiotic back out of the cell
4. Destruction of antibiotics

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13
Q

What are the mechanisms of resistance (4)

A
  1. innate resistance
  2. altered targets
  3. destruction of antibiotic
  4. efflux pumps
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