Antimicrobial Therapy and infection control Flashcards
Do Glycopeptides treat Gram ve- or Gram Ve + or both
positive
Do quinolones treat Gram ve- or Gram Ve + or both
both
Do tetracyclines treat Gram ve- or Gram Ve + or both
both
Do macrolides treat Gram ve- or Gram Ve + or both
mostly positive
some negative
Do aminoglycosides treat Gram ve- or Gram Ve + or both
negative
Do penicillins treat Gram ve- or Gram Ve + or both
positive and negative cocci
Do cephalosporins treat Gram ve- or Gram Ve + or both
both
Do carbapenems treat Gram ve- or Gram Ve + or both
both
Do lincosamides treat Gram ve- or Gram Ve + or both
positive
Do sulfonamides treat Gram ve- or Gram Ve + or both
both
Does isoniazid treat Gram ve- or Gram Ve + or both
both
What are the current challenges with antimicrobial resistance (4)
Resistance plasmids can bring about:
1. Antibiotic degrading enzyme
2. Antibiotic-altering enzyme
3. antibiotic efflux pump - spits antibiotic back out of the cell
4. Destruction of antibiotics
What are the mechanisms of resistance (4)
- innate resistance
- altered targets
- destruction of antibiotic
- efflux pumps