Antiretroviral Drugs- (Nucleotide Inhibitors) Flashcards

1
Q

Tenofovir (viread) is a…

A

Tenofovir disproxilfumarate is a prodrug converted to tenofovir- acyclic nucleoside phosphonate analog of adenosine

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2
Q

Tenofovir MOA:

A

inhibits HIV reverse transcriptase and causes chain termination during elongation of DNA synthesis

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3
Q

Oral absorption of Tenofovir is increased when…

A

it is taken with a fatty meal

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4
Q

Tenofovir is indication for…

A

combination use with other anti-retroviral drugs

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