Antiretroviral Drugs- (Nucleotide Inhibitors) Flashcards
1
Q
Tenofovir (viread) is a…
A
Tenofovir disproxilfumarate is a prodrug converted to tenofovir- acyclic nucleoside phosphonate analog of adenosine
2
Q
Tenofovir MOA:
A
inhibits HIV reverse transcriptase and causes chain termination during elongation of DNA synthesis
3
Q
Oral absorption of Tenofovir is increased when…
A
it is taken with a fatty meal
4
Q
Tenofovir is indication for…
A
combination use with other anti-retroviral drugs