Antipsychotics Flashcards
When should someone stay on antipsychotics forever?
In someone with schizophrenia.
What things should be monitored annually for someone taking clozapine?
Weight
Blood lipids
Fasting blood glucose
Prolactin
What are the side effects of typical antipsychotics?
Extrapyramidal side effects
Neuroleptic malignant syndrome
Hyperprolactinaemia
Prolonged QT interval
What can be used in the treatment of opioid dependence?
Sublingual buprenorphine
Oral methadone
Sublingual Buprenorphine with naloxone
What disease are antipsychotics used as a prophylaxis for?
Schizophrenia
Which condition uses mood stabilisers instead of antipsychotics as a prophylaxis?
Bipolar disorder
What medication is used in sometimes 1st presentation of a manic episode?
Lithium
What medication is used in a manic episode where Pt has a history of mania and depression?
Mood stabiliser
What situations are antipsychotics good for?
Active manic patients - because they have a sedative effect.
Used lots in acute setting.
When acute mania is controlled, what medication is used?
Acute phase - antipsychotic
After acute phase (prophylaxis) - mood stabiliser for maintenance
What other conditions use antipsychotics?
Psychotic depression
Augmenting agent in resisting anxiety
Bipolar - when psychosis is present
What are the two groups of typical antipsychotics?
High potency typically
Low potency typically
What are the side effects of the high potency typical antipsychotics?
EXTRAPYRAMIDAL:
Parkinsonian (muscle rigidity, bradykinesia, tremors)
Akathisia (restlessness)
Dystonia
Other:
orthostatic hypotension
Hyperprolactinaemia
What are the side effects of the low potency typical antipsychotics?
Sedation
Hypotension
Dry mouth
Blurred vision
What are the side effects of atypical antipsychotics?
Weight gain Diabetes Dyslipidaemia Increased cardiovascular risk hypercholesterolaemia
