Antimicrobials Flashcards

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1
Q

Beta lactam

Glycopeptides

A

Inhibit Cell Wall synthesis

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2
Q
Aminoglycosides
Tetracyclines
Macrolides
Chloramphenicol
Oxazolidinones
A

Inhibit protein synthesis

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3
Q

Fluoroquinolones

Nitromidazoles

A

Inhibit DNA Synthesis

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4
Q

Rifamycin

A

Inhibit RNA sythesis

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5
Q

Polymyxin

Cyclic Lipopeptide

A

Cell membrane toxin

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6
Q

Sulfonamides

Diaminopyrimidines

A

Inhibit Folate metabolism

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7
Q

Four mechanisms of Abx resistance

A
BEAT
Bypass Abx sensitive step
Enzyme mediated inactivation
impairment of Accumulation
modification og the drug's Target in the microbe
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8
Q

S aureus skin

A

Flucloxacillin

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9
Q

Pharyngitis Beta-Haemolytic Strep

A

Benzylpenicillin

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10
Q

CAP Mild

A

Amoxicillin

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11
Q

CAP Severe

A

Cefuroxime

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12
Q

HAP

A

Cefuroxime

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13
Q

Bacterial Meningitis

Meningococcus/Streptococcus

A

Ceftriaxone

Amox if Listeria

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14
Q

Community UTI

A

Trimethoprim 3 days

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15
Q

Nosocomial UTI

A

Augmentin or Cephalexin

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16
Q

Sepsis severe

A

Cefuroxime, Metronidazole, +/- Gent

17
Q

Neutropenic sepsis

A

Taz and Gent

18
Q

Colitis C DIfficile

A

Metronidazole stop Ceph