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Pharmacology > Antihypertension > Flashcards

Antihypertension Flashcards

1
Q

Guanabenz

A

Reduce central sympathetic outflow

Treat
Hypertension

Side effect
Sedative
Endocrine problem
Na/H2O retention
Rebound hypertension

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2
Q

Guanfacine

A

Reduce central sympathetic outflow

Treat
hypertension

Side effect
Sedative
Endocrine problem
Na/H2O retention
Rebound hypertension

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3
Q

Guanadrel

A

Treat
Hypertension

Side effect
Interfere with tricyclic antidepressants

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4
Q

Benazepril

A

Inhibit ACE convert angiotensin I to angiotensin II

Treat
Hypertension

Side effect
Hyperkalemia (with thiadize)
Dry cough (bradykinin 無法分解）
Angioedema 水腫
Teratogenesis 畸胎（孕婦不能用）

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5
Q

Captopril

A

Inhibit ACE convert angiotensin I to angiotensin II
Vasodilation

Treat
Hypertension
CHF

Side effect
Hyperkalemia (with thiadize)
Dry cough (bradykinin 無法分解）
Angioedema 水腫
Teratogenesis 畸胎（孕婦不能用）
Headache
Palpitation 心悸
Tachycardia
Fluid retention

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6
Q

Enalapril

A

Inhibit ACE convert angiotensin I to angiotensin II
Vasodilation

Treat
Hypertension
CHF

Side effect
Hyperkalemia (with thiadize)
Dry cough (bradykinin 無法分解）
Angioedema 水腫
Teratogenesis 畸胎（孕婦不能用）
Headache
Palpitation 心悸
Tachycardia
Fluid retention

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7
Q

Fosinopril

A

Inhibit ACE convert angiotensin I to angiotensin II

Treat
Hypertension

Side effect
Hyperkalemia (with thiadize)
Dry cough (bradykinin 無法分解）
Angioedema 水腫
Teratogenesis 畸胎（孕婦不能用）

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8
Q

Lisinopril

A

Inhibit ACE convert angiotensin I to angiotensin II
Vasodilation

Treat
Hypertension
CHF

Side effect
Hyperkalemia (with thiadize)
Dry cough (bradykinin 無法分解）
Angioedema 水腫
Teratogenesis 畸胎（孕婦不能用）
Headache
Palpitation 心悸
Tachycardia
Fluid retention

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9
Q

Quinapril

A

Inhibit ACE convert angiotensin I to angiotensin II

Treat
Hypertension

Side effect
Hyperkalemia (with thiadize)
Dry cough (bradykinin 無法分解）
Angioedema 水腫
Teratogenesis 畸胎（孕婦不能用）

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10
Q

Ramipril

A

Inhibit ACE convert angiotensin I to angiotensin II

Treat
Hypertension

Side effect
Hyperkalemia (with thiadize)
Dry cough (bradykinin 無法分解）
Angioedema 水腫
Teratogenesis 畸胎（孕婦不能用）

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11
Q

Azilsartan

A

ARB (angiotensin receptor block)

Cause
Inhibit vasoconstriction
Reduce TPR, reduce BP
Inhibit ADH, inhibit Na/H2O retention, vessel tension decrease, reduce BP

Treat
Hypertension

Side effect
Hyperkalemia (with thiadize)
Angioedema (水腫）
Teratogenesis 畸胎 (孕婦不能用）

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12
Q

Candesartan

A

ARB (angiotensin receptor block)

Cause
Inhibit vasoconstriction
Reduce TPR, reduce BP
Inhibit ADH, inhibit Na/H2O retention, vessel tension decrease, reduce BP

Treat
Hypertension

Side effect
Hyperkalemia (with thiadize)
Angioedema (水腫）
Teratogenesis 畸胎 (孕婦不能用）

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13
Q

Eprosartan

A

ARB (angiotensin receptor block)

Cause
Inhibit vasoconstriction
Reduce TPR, reduce BP
Inhibit ADH, inhibit Na/H2O retention, vessel tension decrease, reduce BP

Treat
Hypertension

Side effect
Hyperkalemia (with thiadize)
Angioedema (水腫）
Teratogenesis 畸胎 (孕婦不能用）

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14
Q

Irbesartan

A

ARB (angiotensin receptor block)

Cause
Inhibit vasoconstriction
Reduce TPR, reduce BP
Inhibit ADH, inhibit Na/H2O retention, vessel tension decrease, reduce BP

Treat
Hypertension

Side effect
Hyperkalemia (with thiadize)
Angioedema (水腫）
Teratogenesis 畸胎 (孕婦不能用）

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15
Q

Losartan

A

ARB (angiotensin receptor block)

Cause
Inhibit vasoconstriction
Reduce TPR, reduce BP
Inhibit ADH, inhibit Na/H2O retention, vessel tension decrease, reduce BP

Treat
Hypertension

Side effect
Hyperkalemia (with thiadize)
Angioedema (水腫）
Teratogenesis 畸胎 (孕婦不能用）

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16
Q

Olmesartan

A

ARB (angiotensin receptor block)

Cause
Inhibit vasoconstriction
Reduce TPR, reduce BP
Inhibit ADH, inhibit Na/H2O retention, vessel tension decrease, reduce BP

Treat
Hypertension

Side effect
Hyperkalemia (with thiadize)
Angioedema (水腫）
Teratogenesis 畸胎 (孕婦不能用）

17
Q

Telmisartan

A

ARB (angiotensin receptor block)

Cause
Inhibit vasoconstriction
Reduce TPR, reduce BP
Inhibit ADH, inhibit Na/H2O retention, vessel tension decrease, reduce BP

Treat
Hypertension

Side effect
Hyperkalemia (with thiadize)
Angioedema (水腫）
Teratogenesis 畸胎 (孕婦不能用）

18
Q

Valsartan

A

ARB (angiotensin receptor block)

Cause
Inhibit vasoconstriction
Reduce TPR, reduce BP
Inhibit ADH, inhibit Na/H2O retention, vessel tension decrease, reduce BP

Treat
Hypertension

Side effect
Hyperkalemia (with thiadize)
Angioedema (水腫）
Teratogenesis 畸胎 (孕婦不能用）

19
Q

Alpha-methyltyrosine

A

Inhibit NE synthesis
(Tyrosine to L-DOPA)

Treat
Hypertension

Side effect
姿勢性低血壓
鼻塞
射精延遲
GI activity increase

20
Q

Carbidopa

A

Inhibit NE synthesis
(L-DOPA to DA)

Treat
Hypertension
Parkinson disease (with levodopa)

Side effect
姿勢性低血壓
鼻塞
射精延遲
GI activity increase

21
Q

Disulfiram

A

Inhibit NE synthesis
(DA to NE)

Treat
Hypertension

Side effect
姿勢性低血壓
鼻塞
射精延遲
GI activity increase

22
Q

Nitroglycerin & nitrate

A

Vasodilator
Increase NO, cGMP

Treat
心絞痛必備
CHF
Raynaud’s disease

Side effect
Headache
Palpitation 心悸
Tachycardia
Fluid retention

23
Q

Hydralazine

A

NO increase
Vasodilation

Treat
Hypertension
CHF

Side effect
Headache
Palpitation 心悸
Tachycardia
Fluid retention
Lupus syndrome 紅斑性狼瘡
（autoimmune)

24
Q

Minoxidil

A

Vasodilation

Treat
hypertension
雄性禿

Side effect
Headache
Palpitation 心悸
Tachycardia
Fluid retention
多毛症

25
Q

Sodium nitroprusside

A

IV only
Vasodilator

Treat
Emergency hypertension crisis
Acute CHF

Side effect
Headache
Palpitation 心悸
Tachycardia
Fluid retention

26
Q

Diazoxide

A

Open K+ channel
急救用

Treat
Emergency hypertension
腎上腺髓瘤
高血壓腦病
主動脈剝離
腦出血

Pharmacology (8 decks)

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