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Pharmacology > Adregenic Agonist > Flashcards

Adregenic Agonist Flashcards

1
Q

Phenylephrine

A

Alpha 1

Treat
陣發性心房心搏過速
鼻塞
散瞳劑

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2
Q

Midodrine

A

Alpha 1

Treat
姿勢性低血壓

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3
Q

Clonidine

A

Alpha 2
Cross BBB

Cause
NE BP decrease, not renal BP
Reduce central sympathetic outflow

Treat
Hypertension
過動
減輕戒斷症狀
鴉片類止痛劑
安眠藥

Side effect
Rebound hypertension (突然停藥）
Sedative
Endocrine problem
Na/H2O retention

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4
Q

Methyldopa

A

Alpha 2

Treat
高血壓孕婦

Side effect
假陽性 Coombs test result (RBC IgG)

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5
Q

Tizanidine

A

Alpha 2

Cause
Reduce CNS glutamate
Decrease motor
Little 降血壓

CNS muscle relaxant
解痙攣藥

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6
Q

Dobutamine

A

Beta 1
強心劑

Treat
急性心衰竭

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7
Q

Terbutaline

A

Beta 2

Treat
Asthma
Prevent preterm

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8
Q

Ritodine

A

Beta 2
>20 week 安胎劑
瘦肉精

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9
Q

Mirabegron

A

Beta 3
減肥藥

Treat
膀胱過動症

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10
Q

Fenoldopam

A

D1

Treat
手術後急性高血壓

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11
Q

Isoproterenol

A

Beta 12

Cause
BP decrease, HR increase
Vasodilation

Treat
Asthma
Cardiogenic shock
焦慮/疲倦

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12
Q

Epinephrine

A

Alpha 12 Beta 12

(Low dose) cause
BP decrease, HR increase

Treat
過敏性休克首選
Asthma
Prolong topical anesthesia
Glaucoma

(High dose) cause
BP increase, HR decrease
上升血糖

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13
Q

Norepinephrine

A

Alpha 12 Beta 1

Cause
BP increase, HR decrease
腎血流下降

Treat
Shock
急性低血壓

Side effect
心律不整
出血
水腫
皮膚變白脫落(Phentolamine 治療）

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14
Q

Dopamine

A

Alpha 1 Beta 1 D1

(Low dose) cause
BP decrease, HR increase
腎臟 內臟動脈擴張

Treat
急性休克首選

(High dose) cause
BP increase, HR decrease
缺血性壞疽

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15
Q

Amphetamine

A

Cross BBB, releasing agent

Cause
NE & DA & Epi increase
appetite decrease
Inhibit MAO

Treat
過動
Narcolepsy (發作性睡病）

Side effect
精神分裂(chlorpromazine 治）
中毒用haloperidol 治

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16
Q

Tyramine

A

Cross BBB, releasing agent

Cause
NE & DA increase
appetite decrease

17
Q

Methylphenidate

A

Releasing agent
Amphetamine 衍生物
降低食慾

Treat
過動
Narcolepsy

Side effect
精神分裂（chlorpromazine 治）
中毒（haloperidol治）

18
Q

Cocaine

A

Inhibit uptake
Inhibit NE & DA recycling
Topical anesthesia

19
Q

Ephedrine 麻黃鹼

A

Cross BBB

Cause
Increase NE, BP

Act as
Bronchodilator
散瞳

Treat
鼻塞
慢性氣喘
感冒
尿床

常作為禁藥

20
Q

Pseudoephedrine

A

Treat
過敏性鼻炎
鼻塞
中耳炎
尿床

常作為禁藥

21
Q

Metaraminol

A

Treat
急性低血壓
休克

22
Q

Phenylpropanolamine

A

不賣

Treat
鼻塞
減肥藥

23
Q

Albuterol

A

Beta 2

Treat
COPD
Asthma

24
Q

Bitolterol

A

Beta 2

Treat
COPD
Asthma

25
Q

Metaproterenol

A

Beta 2

Treat
COPD
Asthma

26
Q

Methoxamine

A

Alpha 1

Cause
BP increase

Treat
陣發性心搏過速 (PSVT)

27
Q

Oxymetazoline

A

Alpha

Treat
鼻塞

28
Q

Modafinil

A

Inhibit NE DA recycle

Treat
Narcolepsy

29
Q

Brimonidine

A

Alpha 2

Treat
Glaucoma

Pharmacology (8 decks)

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