Antifungals Flashcards by Emma ridpath | Brainscape

Q

Superficial mycoses affect…

A

Skin
Nails
Scalp
Mucous membrane

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Q

Systemic mycoses affect…

A

Internal organs

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Q

Components that make up fungal cell wall

A

Glucan, chitin, manan

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Q

Fungal plasma membrane contains

A

Ergosterol

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Q

Human plasma membrane contains

A

Cholesterol

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Q

Caspofungin

A

Echinocandin

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Q

Micafungin

A

Echinocandin

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Q

Echinocandins work by

A

Fungicidal

Block b13glucan synthesis

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Q

Polyene anti fungal works by

A

Binding to resident Ergosterol

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Q

Amphotericin b

A

Polyene anti fungal

Prolonged use severe SE

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Q

Mystatin

A

Polyene anti fungal

Oral gi infections

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Q

Lonosetrol demethylation is essential for…

A

Ergosterol biosynthesis

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Q

Azoles

A

Imidazole
Triazole

Block lonosetrol demethylation

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Q

Most potent Azoles?

A

Triazoles

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Q

Flucytosine

A

Anti fungal targets DNA RNA

Taken up by cell an prevents DNA synthesis

Hugh levels of resistance

Given with Azoles

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Q

Mycoses are…

A

Fungal diseases