Antiemetics Flashcards
Droperidol Dose + Trade Name
Inapsine
0.625 mg
Promethazine Dose + Trade Name
Phernergan
6.25 - 25 mg
Ondansetron Dose + Trade Name
Zofran
4 mg
Dexamethasone Dose + Trade Name
Decadron
4 mg
Metoclopramide Dose + Trade Name
Reglan
10 - 20 mg
Scopolamine Dose
Patch
Droperidol Onset
1 - 5 min
Droperidol Duration
2 - 3 hours
Promethazine Onset
1 - 5 min
Promethazine Duration
4 - 6 hours
Ondansetron Onset
10 min
Ondansetron Duration
4 - 9 hours
Dexamethasone Onset
10 - 30 min
Dexamethasone Duration
2 - 10 hours
Metoclopramide Onset
10 min
Metoclopramide Duration
2 hrs
Scopolamine onset
2 - 4 hours
Scopolamine duration
72 hrs
Propofol PONV Dose & MOA
10 - 15 mg IV, then 10 mcg/kg/min gtt
Blocks serotonin release at 5HT3 receptors
May also inhibit CTR
Scopolamine MOA
Anticholinergic
Competitive antagonist of mACh receptors
decreases secretions and GI motility
Droperidol MOA
Dopamine (D2) Antagonist
Promethazine MOA
H1 antagonist
Dopamine antagonist
Ondansetron MOA
5HT3 Antagonist
Blocks serotonin @ CTZ
Metoclopramide MOA
Dopamine antagonist
Stimulates gastric motility