Antidysrhythmics II LOLS

Question 1

action of antidysrhythmic drugs

Answer 1

depress contractility, excitability and automaticity; block adrenergic (sympathetic) simulation; incrase repolarization (phase to move to refractory/rest phase)

Question 2

define action potential

Answer 2

when there is movement of Na and K across cell membrane that causes depolarization/contraction

Question 3

define refractory phase

Answer 3

resting state; phase 4 of action potential; cell CANNOT respond to new stimulus; K is inside and Na is outside once again

Question 4

define automaticity

Answer 4

electrical impulse formation

Question 5

define excitability or irritability

Answer 5

cell CAN respond to stimulus

Question 6

define depolarization

Answer 6

muscle activated; contraction starts; systole to eject blood; Na rushing inside and Ca joined in, while K moving outside; phase starts at 0

Question 7

define repolarization

Answer 7

movement towards refractory/resting phase; K is completely out now; phase starts at 1 and plateaus at phase 2 and continues to phase 3 of action potential

Question 8

the phase between repolarization and refractory phase?

Answer 8

phase 3; magnesium activates the Na-K pump to fascilitate the movement of K back into the cell; Na and Ca move out; when complete, refractory phase 4 has been reached.

Question 9

define refractory phase

Answer 9

resting state; diastole to fill in with blood; phase 4 of action potential; cell CANNOT respond to new stimulus; K is inside and Na is outside once again

Question 10

antidysrhythmic class II drugs are the

Answer 10

beta blockers LOLS

Question 11

what do class II beta blockers do

Answer 11

diminish sympathetic nervous system response; DEPRESS PHASE 4 refractory/rest phase OF ACTION POTENTIAL (SLOW IT DOWN); remember beta blockers have (-) inotropes that weaken contractility

Question 12

class II beta blockers contraindication

Answer 12

sinus bradycardia; AV BLOCK

Question 13

3 examples of class II beta blockers

Answer 13

acebutolol (selective), esmolol (selective), PROPANOLOL (non selective)

Question 14

indication of class II non selective beta blocker PROPANOLOL

Answer 14

SUPRAVENTRICULAR TACHYCARDIA (HR 100-300 bpm) aka PSVT; dysrhythmia originate from foci above the bifurcation of Bundle of His (could be AV or SA node problem)

Question 15

nsg consideration with non selective beta blockers

Answer 15

glycogenolysis/breakdown glycogen to make glucose/increase BG and mask hypoglycemia; bronchospasm/constriction

Question 16

bronchospasm from non selective beta blockers sounds like

Answer 16

wheezing