Antidysrhythmics Ia Norpace

Question 1

action of antidysrhythmic drugs

Answer 1

depress contractility, excitability and automaticity; block adrenergic (sympathetic) simulation; incrase repolarization (phase to move to refractory/rest phase)

Question 2

define action potential

Answer 2

when there is movement of Na and K across cell membrane that causes depolarization/contraction

Question 3

define refractory phase

Answer 3

resting state; phase 4 of action potential; cell CANNOT respond to new stimulus; K is inside and Na is outside once again

Question 4

define automaticity

Answer 4

electrical impulse formation

Question 5

define excitability or irritability

Answer 5

cell CAN respond to stimulus

Question 6

define depolarization

Answer 6

muscle activated; contraction starts; systole to eject blood; Na rushing inside and Ca joined in, while K moving outside; phase starts at 0

Question 7

define repolarization

Answer 7

movement towards refractory/resting phase; K is completely out now; phase starts at 1 and plateaus at phase 2 and continues to phase 3 of action potential

Question 8

the phase between repolarization and refractory phase?

Answer 8

phase 3; magnesium activates the Na-K pump to fascilitate the movement of K back into the cell; Na and Ca move out; when complete, refractory phase 4 has been reached.

Question 9

define refractory phase

Answer 9

resting state; diastole to fill in with blood; phase 4 of action potential; cell CANNOT respond to new stimulus; K is inside and Na is outside once again

Question 10

Sodium channel blockers does this

Answer 10

decrease fast influx of Na into cell; depress past 0 of action potential; effect is decrease automaticity/formation and conduction of electrical stimulus

Question 11

indication of sodiume channel blockers

Answer 11

tx L/T dysrhythmias

Question 12

contraindications of sodium channel blockers

Answer 12

cardiogenic SHOCK; 2nd or 3rd AV BLOCK; GLAUCOMA; caution cardiomyopathy, renal, hepatic d/o

Question 13

nsg responsibilities with sodium channel blockers

Answer 13

PC HF, hypokalemia, hypernatremia (?)

Question 14

sodium channel blockers are divided into 3 subgroups

Answer 14

Ia, Ib, Ic

Question 15

sodium channel blocker Subclass Ia does this

Answer 15

slow conduction and prolong repolarization

Question 16

example of subclass Ia drug

Answer 16

Norpace

Question 17

Sublcass Ia Norpace indication

Answer 17

Vetricular Tachycardia and Premature Ventricular Contractions; remember Ia slows conduction and prolong repolarization; you’re that much further away from having another depolarization

Question 18

subclass Ia Norpace a/e

Answer 18

precipitate CHF (r/t decreased heart pump) and hypotension

Question 19

subclass Ia Norpace contraindication

Answer 19

cardiogenic SHOCK; 2nd or 3rd AV BLOCK; GLAUCOMA; caution cardiomyopathy, renal, hepatic d/o

Question 20

subclass Ia Norpace is a BBW, so use it on pts that are

Answer 20

at risk of dying anyway; got nothing to lose at this point

Question 21

with subclass Ia Norpace, if pt is dizzy check what?

Answer 21

HR and BP