Antidysrhythmics

Question 1

Membrane Stabilizing Drugs - Lidocaine

Answer 1

Class 1B

MOA - blocks sodium channels - aka accelerates depolarization

Use: Ventricular dysrhythmias (only give IV form for dysrhythmias)

AEs: bradycardia, hypotension, anxiety, METALLIC TASTE

Don’t use: advanced heart block (when there’s really low atrial beating so only ventricles are working)

Interactions: antifungals, erythromycin

NCs:

Question 2

Increase Action Potential - Amiodarone

Answer 2

Class III

MOA - prolong refractory period (QT interval)

Use: Supraventricular and ventricular dysrhythmias and V fib, and MAYBE Atrial Fibrillation

AEs: PULMONARY TOXICITY (leads to pulmonary fibrosis), BLUE/GRAY SKIN COLOR, brady and hypotension

Interactions: digoxin (increase of dig in blood), warfarin (increases INR), haloperidol (causes too long QT interval)

***stays in body for up to 30 days

Question 3

Beta Blockers - Metoprolol

Answer 3

Class II

very effective with electrical nodes and pathways, so use for sinus tachycardia

PO and IV

Question 4

Calcium Channel Blockers - Diltiazam

Answer 4

Class IV

it has rapid ventricular response so ….

Use: for ACUTE situations; 1ST line drugs for atrial fib and a flutter and PSVT

Question 5

Cardiac Glycoside - Digoxin

Answer 5

Only digoxin used as antidysrhythmic in this class

Use: for CHRONIC atrial fib; DON’T use in pts with Vtach or Vfib

Oral and IV