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step 1 quick hits > antidotes and adverse drug reactions > Flashcards

antidotes and adverse drug reactions Flashcards

1
Q

acetominophen

A

N-acetyl cysteine (replenishes glutatione - donates sulfahrydly groups )

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2
Q

salicyclate antidote

A

NaHCO3 (alkalanize urine), dialysis

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3
Q

amphetamine (basic)

antidote

A

NH4CL (acidify urine)

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4
Q

acetylcholineesterase inhibitors, organophosphates

A

atropine, pralidoxine (regenerates Acetyl choline esterase)

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5
Q

anti-muscaraninc, anticholinergic

antidotie

A

physostigime salicyclate, control hyperthermia

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6
Q

b-blockers antidote

A

glucagon

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7
Q

digitalis antidote

KLAM

A

normalize K+

Lidocaine

Anti-dig FAb fragments

Mg2+

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8
Q

iron antidote

A

deferoxamine

deferasirox

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9
Q

lead antidote

A

CaEDTA, dimercaprol, succimier, penicillamine

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10
Q

mercury, asrenic, gold antidote

A

dimercarprol (BAL)

succimer

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11
Q

copper, arsenic gold antidote

A

penicillamine

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12
Q

cyanide antidote

A

nitrite+ thiosulfate, hydroxycobalamin

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13
Q

methemoglobin antidote

A

methylene blue + vitamin C

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14
Q

carbon monoxide antidote

A

100 % O2

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15
Q

methanol

ethylene glycol (antifreeze) antidote

A

fomepizole >ethanol, dialysis

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16
Q

methanol, ethylene glycol antidote

A

fomepizole>> ethanol, dialysis

17
Q

opiods antidote

A

naloxone/naltrexone

18
Q

benzodiazepines antidotes

A

flumazenil

19
Q

TCA antidotes

A

NaHCO3- (plasma alkalinization)

20
Q

heparin antidote

A

protamine

21
Q

warfarin antidotes

A

vitamin K, fresh frozen plasma

22
Q

tPA, streptokinase, urokinase antidote

A

aminocaproic acid

23
Q

theophylline antidote

A

beta- blocker

step 1 quick hits (15 decks)

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