Anticoagulantes Flashcards

1
Q

Antídoto de heparina

A

Protamina

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2
Q

Tipo de heparina que no actúa directamente contra la trombina

A

Heparina de bajo peso molecular
Enoxaparina
Fondaparinux

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3
Q

Antídoto de
Rivaroxaban
Apixaban

A

Adexanet alfa

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4
Q

MA de heparina

A

Potencia el efecto de la antitrombina III

Inhibe factor X y IIa

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5
Q

MA de heparina

A

Potencia el efecto de la antitrombina III

Inhibe factor X y IIa

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6
Q

Antídoto de la warfarina

A

Vitamina K - FITOMEDIADONA

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7
Q

EA de la heparina

A
  • Hemorragia
  • HIT I
  • HIT 2

HIT 1: Trombocitopenia inducida por heparina

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8
Q

Tipo de anticoagulante permitido en el embarazo

A

Heparina: no atraviesa BHE

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9
Q

Antídoto de
DABIGATRAN

A

IDARUCIZUMAB

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10
Q

Fármaco que es preventivo

A

Warfarina, tarde de 3 a 5 días en hacer efecto

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11
Q

EA del dabigatran

A

Disepsia
Gastritis
Hemorragia

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12
Q

Es un inhibidor directo de la trombina IIA

A

Dabigatran

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13
Q

MA de
RIVAROXABAN
APIXABAN

A

Inhiben directamente el factor Xa

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14
Q

Anticoagulantes con excreción renal

A

Fondaparinux, enoxaparina
Dabigatran

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15
Q

Qué fármaco afecta el tiempo de TTP (tromboplastina) ?

A

Heparina
Lo aumenta de 1.5 a 2 veces más

Normla: 25-35, heparina: 50-90

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16
Q

EA de la warfarina

A
  • Hemorragia
  • Sx fetal por warfarina: aborto, anomalías congénitas
17
Q

Fármacos trombocitolíticos

A
  • Alteplase
  • Tenecteplase
  • Estreptoquinasa
18
Q

Antídoto de los fármacos trombolíticos

A

Acido aminocaproico
Acido tranexámico

19
Q

EA de los fármacos trombolíticos

A
  • Hemorragia
  • Estreptocinasa derivada de estreptococo –> reacción alergica
20
Q

Anticoagulante indicado en cirugía ortopédica mayor

A

Dabigatrán