Antibody Structure Flashcards
Top:N-Terminus
Bottom: C-Terminus
Heavy Chains letters?
G, A, M, E, D
Which chain determines which antibody class is it?
Heavy chain
An antibody is made up of
4 polypeptide chains
The arms of the Y (antibodies)
have two divisions.
Name both?
2 Inner variable heavy
2 outer variable light
2 inner constant heavy
2outer constant light
The body of bottom half of the Y (antibodies)
have two divisions.
Name both?
2 constant heavy
CHO
Glycosylation
Attached to C(h)2
The second constant heavy
What binds to antigen?
Complementary Determining Regions(CDR)
2 identical light chains have a mass of
25KDa
Kilodaltons
2 identical heavy chains have a mass of
50KDa
Light chain is bond to heavy chain by
Disulfide bonds
The first___________ of amino terminal vary of H and L are Variables.
100a/a
The heavy chain on the arms of the Y(antibody) are also called the ___________ region
Fab
There is two of them because there is 2 heavy chains
The heavy chain on the body of the Y(antibody) are also called the ___________ region
Fc
The FC region binds to the
FCR
FC receptors
