Antibody-guided imaging of cancer Flashcards
what can be used in nuclear medicine to locate cancer cells or infections using molecular imaging
radio-labelled antibodies
what type of molecular imaging used
CT, MRI, PET, PET/CT, PET/MRI
which elements are used as radio-pharmaceuticals to image cancers
- 111 Indium
- 68Ga
- 89Zr
Labelled antibodies
examples of an antibody used to guide imaging of cancer
Capromab
Capromab
reacts with prostate membrane specific antigens on prostate cells
Capromab is conjugated to
111Indium with chelator pendetide and radio-labeled antibody used to locate cancerous prostate cells
thernostics
therapy and diagnostics
example of a thernostic tool
89Zr-labeled-Rituximab-PET
89Zr-labeled-Rituximab-PET as an
imaging biomarker to assess CD20 targeting
name of antibody used to trace primary prostate cancer
68Ga-PSMA–PET–CT