Antibody-guided imaging of cancer Flashcards

1
Q

what can be used in nuclear medicine to locate cancer cells or infections using molecular imaging

A

radio-labelled antibodies

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2
Q

what type of molecular imaging used

A

CT, MRI, PET, PET/CT, PET/MRI

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3
Q

which elements are used as radio-pharmaceuticals to image cancers

A
  • 111 Indium
  • 68Ga
  • 89Zr

Labelled antibodies

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4
Q

examples of an antibody used to guide imaging of cancer

A

Capromab

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5
Q

Capromab

A

reacts with prostate membrane specific antigens on prostate cells

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6
Q

Capromab is conjugated to

A

111Indium with chelator pendetide and radio-labeled antibody used to locate cancerous prostate cells

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7
Q

thernostics

A

therapy and diagnostics

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8
Q

example of a thernostic tool

A

89Zr-labeled-Rituximab-PET

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9
Q

89Zr-labeled-Rituximab-PET as an

A

imaging biomarker to assess CD20 targeting

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10
Q

name of antibody used to trace primary prostate cancer

A

68Ga-PSMA–PET–CT

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