Antibiotics Lecture 31 Flashcards
1
Q
Aminoglycosides Types Mechanism Cidal or Static MOR Toxicity
A
GNATS G=Gentamycin N=neomycin A=amikacin T=tobramycin S=streptomycin
30S
Peak Dependent
Cidal
Bacterial transferase enzymes inactivate the drug by acetylation, phosphorylation, adenylation
NNOT Nephrotoxicity Neuromuscular Blockage Ototoxicity Teratogen
2
Q
Gentacmicin
A
- Gram Neg (Pseudo)
2. Gram Positive
3
Q
Tobramycin
A
Pseudo
4
Q
Amikacin
A
- Gram Negative (generally best at negative except for pseudo, Tobro is master)
- mycobacterial (atypical)
5
Q
Streptomycin
A
- Gram Positive (Enterococcus)
2. Mycobacterial (less atypical than Amikacin)
6
Q
Gram Negative
A
GAT genta amika tobra HIGH DOSE
7
Q
Gram positive
A
GS
Genta
Strepto
Low dose sufficient
8
Q
Mycobacterial
A
AS
Amika
Strepto
