antibiotics

Question 1

macrolides

Answer 1

azithromycin, erythromycin, clarithromycin (c.diff)
protein synthesis
intracellular organisms - legionella
no cell wall - mycoplasm, chlamydia

Question 2

clindamycin

Answer 2

protein synthesis
2nd line staph and strep
anaerobes

Question 3

choramphenicol

Answer 3

protein synthesis

eye infections

Question 4

piperacillin/tazobactam

Answer 4

penicillin
cell wall
IV negative
not MRSA

Question 5

C.difficile

Answer 5

co-amoxiclav
cephalosporin
fluroquinolones
clarithromycin

Question 6

cephalosporins

Answer 6

cef in name
cell wall
c.diff
broad spectrum

Question 7

glycopeptides

Answer 7

vancomycin, teicoplanin
IV
positive 
treat c.diff
cell wall

Question 8

aminoglycosides

Answer 8

gentamycin IV 
toxic 
protein synthesis
negative aerobic coliforms 
pseudomonas 
not in pregnancy

Question 9

amaxicillin

Answer 9

IV, oral
negative
penicillin
cell wall

Question 10

flucloxacillin

Answer 10

penicillin 
cell wall
staph and strep 
IV, oral 
positive

Question 11

penicillin

Answer 11

G - IV
V - oral
long lasting - MI

Question 12

fluroquinolones

Answer 12

ciprofloxacin -  UTI, IV, oral 
levofloxacin - severe community acquired pneumonia 
DNA - super coiling enzymes 
broad spectrum 
orally to treat pseudomonas 
c.diff
not in pregnancy

Question 13

tetracyclines

Answer 13

doxycycline
protein synthesis
no cell wall atypical pseudomonas
not in pregnancy

Question 14

trimethoprim

Answer 14

oral alone 
with sulphamethoxazole oral/IV
inhibits folic acid production 
some negative and some positive 
not in first 3 months of pregnancy

Question 15

metronidazole

Answer 15

DNA
oral/IV
anaerobes
not in first 3 months of pregnancy