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DOCs/Indications > Antibiotics > Flashcards

Antibiotics Flashcards

1
Q

HIV + active TB co-infection

A

Rifabutin replaces rifampin in RIPE therapy due to less P450 enzyme induction → less drug interactions

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2
Q

HIV + latent TB co-infection

A

Isoniazid (to avoid rifampin drug interactions)

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3
Q

Moderate to severe Erythema Nodosum Leprosum (Mycobacterium leprae)

A

Thalidomide (non-childbearing potential)

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4
Q

Mycobacterium avium complex

A

Clarithromycin/azithromycin
Ethambutol
A 3rd oral drug: Rifampin, Rifabutin, Ciprofloxacin

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5
Q

Malaria empirical/preventative in pregnant women

A

Pyrimethamine + sulfadoxine

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6
Q

Complicated, chloroquine resistant malaria in pregnant women, children

A

Quinidine gluconate + clindamycin

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7
Q

Radical cure of p vivax + p ovale, Terminal prophylaxis

A

Primaquine

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8
Q

Most systemic fungal infections

A

Amphotericin B

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9
Q

Cryptococcus infections

A

Amphotericin B + Flucytosine (synergistic)

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10
Q

Aspergillus

A

Voriconazole + Amphotericin B

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11
Q

Refractory aspergillus

A

Caspofungin/echinocandins

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12
Q

Fungal meningitis

A

Fluconazole

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13
Q

Onychomycosis

A

Griseofulvin

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14
Q

Symptomatic, invasive Entamoeba histolytica

A

Metronidazole (+luminal amebicide) (2nd tinidazole)

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15
Q

Asymptomatic Entamoeba histolytica

A

Luminal amebicides:
Iodoquinol
Paromomycin
Tetracycline & Erythromycin

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16
Q

Giardia lamblia

A

Metronidazole (2nd tinidazole)

17
Q

Trichomonas vaginalis

A

Metronidazole (2nd tinidazole)

18
Q

Toxoplasma gondii

A

Pyrimethamine + Sulfadiazine + folinic acid (Leucovorin)

19
Q

Pneumocystis jirovecii (also HIV prophylaxis)

A

Trimethoprim + sulfamethoxazole (bactrim) + folinic acid

20
Q

Roundworms/Nematodes

A

Albendazole, Mebendazole, or pyrantel pamoate

21
Q

Fluke/Trematodes

A

Praziquantel

22
Q

Tapeworms/Cestodes

A

Praziquantel

23
Q

Schistosomes

A

Praziquantel

24
Q

Sheep liver flukes

A

Bithionol

DOCs/Indications (7 decks)

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