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Disease and Defense Mine > Antibiotics > Flashcards

Antibiotics Flashcards

1
Q

penicillin

A 
CW synth. blocker
beta lactam antibiotic
elimination: renal
V version: acid stable
G version: prototype
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2
Q

dicloxacillin

A

CW synth. blocker,
penicillinase resistant
beta lactam antibiotic
elimination: renal

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3
Q

amoxacillin/ampicillin

A

CW synth blocker
beta lactam antibiotic
elimination: renal

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4
Q

amox/clav

A

CW synth blocker
penicillinase resistant
beta lactam antibiotic
elimination: renal

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5
Q

pip/tazo

A 
CW synth blocker
penicillinase resistant
beta lactam antibiotic
admin: IV ONLY
elimination: renal
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6
Q

cephalexin (po)

cefazolin (IV)

A

1st gen
CW synth blocker
beta lactam antibiotic
elimination: renal

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7
Q

cefuroxime

A

2nd gen
CW synth blocker
beta lactam antibiotic
elimination: renal

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8
Q

ceftriaxone

A 
3rd gen
CW synth blocker
beta lactam antibiotic
admin: IV ONLY
elimination: renal 
gonorrhea activity
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9
Q

ceftazidime

A 
3rd gen
CW synth blocker
pseudomonas activity
beta lactam antibiotic
elimination: renal
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10
Q

cefepime

A

4th gen
CW synth blocker
beta lactam antibiotic
elimination: renal

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11
Q

ertapenem

A

carbapenem
CW synth blocker
beta lactam antibiotic

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12
Q

imip, dori, mero

A

carbapenem
CW synth blocker
beta lactam antibiotic

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13
Q

vancomycin

A

CW synth blocker

admin: IV only except in entero-infections

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14
Q

macrolides

A

protein synth blocker
azithromycin, clarithromycin, erythromycin
Unique activity: mycoplasma
Interactions: clar & ery drug-drug interactions due to inhibition of P450

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15
Q

tetracyclines

A 
protein syn blocker
doxycycline- non-renally emlinated tetracycline, can lead to candidal overgrowth
adverse effects: candidal overgrowth
elimination: renal
unique activity: mycoplasma
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16
Q

clindamycin

A

protein syn blocker
adverse reaction: C. difficile diarrhea
elimination: non-renal

17
Q

chloramphenicol

A

protein syn blocker

greyed out on chart

18
Q

aminoglycosides

A

protein syn blocker
BACTERICIDAL- irreversibly bind ribosome
admin: IV only
elimination: renal

19
Q

ciprofloxacin

A

fluoroquinolone
DNA syn blocker
elimination: renal, but is non-substrate inhibitor of P450 (caffeine-theophylline)

20
Q

levofloxacin

A

fluoroquinolone

DNA syn blocker

21
Q

moxifloxicin

A

fluoroquinolone

DNA syn blocker

22
Q

nitrofurantoin

A

DNA syn blocker

23
Q

metronidazole

A

DNA syn blocker

Interactions: with alcohol due to inhibition of aldehyde metabolism

24
Q

protein synthesis blockers

A

typically bacteriostatic

25
Q

CW synth inhibitors

A

typically bactericidal

26
Q

DNA inhibitors

A

typically bactericidal

Disease and Defense Mine (12 decks)

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