Antibiotics Flashcards

1
Q

penicillin

A
CW synth. blocker
beta lactam antibiotic
elimination: renal
V version: acid stable
G version: prototype
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

dicloxacillin

A

CW synth. blocker,
penicillinase resistant
beta lactam antibiotic
elimination: renal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

amoxacillin/ampicillin

A

CW synth blocker
beta lactam antibiotic
elimination: renal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

amox/clav

A

CW synth blocker
penicillinase resistant
beta lactam antibiotic
elimination: renal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

pip/tazo

A
CW synth blocker
penicillinase resistant
beta lactam antibiotic
admin: IV ONLY
elimination: renal
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

cephalexin (po)

cefazolin (IV)

A

1st gen
CW synth blocker
beta lactam antibiotic
elimination: renal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

cefuroxime

A

2nd gen
CW synth blocker
beta lactam antibiotic
elimination: renal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

ceftriaxone

A
3rd gen
CW synth blocker
beta lactam antibiotic
admin: IV ONLY
elimination: renal 
gonorrhea activity
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

ceftazidime

A
3rd gen
CW synth blocker
pseudomonas activity
beta lactam antibiotic
elimination: renal
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

cefepime

A

4th gen
CW synth blocker
beta lactam antibiotic
elimination: renal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

ertapenem

A

carbapenem
CW synth blocker
beta lactam antibiotic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

imip, dori, mero

A

carbapenem
CW synth blocker
beta lactam antibiotic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

vancomycin

A

CW synth blocker

admin: IV only except in entero-infections

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

macrolides

A

protein synth blocker
azithromycin, clarithromycin, erythromycin
Unique activity: mycoplasma
Interactions: clar & ery drug-drug interactions due to inhibition of P450

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

tetracyclines

A
protein syn blocker
doxycycline- non-renally emlinated tetracycline, can lead to candidal overgrowth
adverse effects: candidal overgrowth
elimination: renal
unique activity: mycoplasma
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

clindamycin

A

protein syn blocker
adverse reaction: C. difficile diarrhea
elimination: non-renal

17
Q

chloramphenicol

A

protein syn blocker

greyed out on chart

18
Q

aminoglycosides

A

protein syn blocker
BACTERICIDAL- irreversibly bind ribosome
admin: IV only
elimination: renal

19
Q

ciprofloxacin

A

fluoroquinolone
DNA syn blocker
elimination: renal, but is non-substrate inhibitor of P450 (caffeine-theophylline)

20
Q

levofloxacin

A

fluoroquinolone

DNA syn blocker

21
Q

moxifloxicin

A

fluoroquinolone

DNA syn blocker

22
Q

nitrofurantoin

A

DNA syn blocker

23
Q

metronidazole

A

DNA syn blocker

Interactions: with alcohol due to inhibition of aldehyde metabolism

24
Q

protein synthesis blockers

A

typically bacteriostatic

25
Q

CW synth inhibitors

A

typically bactericidal

26
Q

DNA inhibitors

A

typically bactericidal