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Microbial Pharmacology > Antibacterial: Clinical Applications > Flashcards

Antibacterial: Clinical Applications Flashcards

1
Q

What is the First Line Treatment for uncomplicated S&ST infection?

A

Gram (+) Narrow Spec.
Penicillin
1st gen Ceph
Vanco if they’re allergic

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2
Q

What is the First Line Treatment for complicated S&ST infection?

A

G+/-

Penicillin + lactamase inhibitor (ticarcillin/clavulanic acid)

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3
Q

What is the First Line Treatment for MRSA?

A

Vanco, Linezolid, Daptomycin

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4
Q

What is the First Line Treatment for Osteomyelitis?

A

Vancomycin
Cephalosporin
(broad spectrum)

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5
Q

What is the First Line Treatment for Surgical B&Joint Infections?

A

Penicillin + Lactamase inhibitor

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6
Q

What is the First Line Treatment for Septic Arthritis?

A

Ceftriaxone

If MRSA =>VLD

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7
Q

What is the First Line Treatment for Prosthetic Joint?

A

Rifampin (adherent bacteria)

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8
Q

What is the First Line Treatment for acute sinusitis and cronic bronchitis?

A

Amoxicillin + lactamase inhibitor

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9
Q

What is the First Line Treatment for Pharyngitis?

A

Penicillin or Amoxicillin

Cephalosporin if allergic.

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10
Q 
What is the First Line Treatment for Community Acquired bacterial Pneumonia?
Ambulatory
Resistant
Hospitalized
Aspiration
MRSA
A

Ambulatory: Macrolide (broad spec) (erythro, azithro, clarithromycin)
Res: Fleuro (levofloxacin or moxifloxacin)
Hosp:B-Lactam +Macrolide
Aspir: Metro, Clindamycin
MRSA: Vanco, Linezolid

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11
Q

What is the First Line Treatment for Hospital/Healthcare/ventilator associated Pneumonia?

A

Empiric:Cephtriaxone
MRSA: Vanco or Linezolid

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12
Q

What would constitute a complicated S&ST infection?

A

Burns, Diabetes, Pressure Ulcers, trauma/surgical are generally polymicrobial in nature

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13
Q

What is different about Mycoplasma Pneumoniae and how you treat it?

A

It has no peptidoglycan! Can’t treat it with a B-Lactam

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14
Q

What is the First Line Treatment for Uncomplicated UTI?

A

Trimethoprim/Sulfamethoxazole (TMP-SMX)

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15
Q

What is the First Line Treatment for Pyelonephritis and Prostatitis?

A

TMP-SMX

Fluoroquinolones

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16
Q

What is the First Line Treatment for complicated (hospitalized) UTI?

A

Fluoroquinolones

TMP-SMX

17
Q

What is the First Line Treatment for Intra-abdominal Infections?

A

Gram (-) Bacteria

Ticarcillin + Clavulanate

18
Q

What is the First Line Treatment for C. Diff?

A

Metro(mod) and Vanco(severe)

19
Q

What Atbc is associated with formation of C. Diff infection formation?

A

Clindamycin

20
Q

What is the First Line Treatment for Meningitis(Strep Pneumo and neisseria)?

A

3-4 gen Cephalosporins

Ceftriaxone or cefotaxime +Vanco

21
Q

What is the First Line Treatment for Neonatal Meningitis(GBS, G- or lysteria)?

A

Ampicillin + Cephalosporin

sometimes gentamcin for lysteria

22
Q

What is the First Line Treatment for Sepsis?

A

3-4 Gen Cephalosporin

+VANCO

23
Q

What is the Drug that can be used for Gram + Spore Forming Bacteria?

A

Vancomycin

24
Q

What is the First Line Treatment for Endocarditis?

A

Cipro + Amoxicillin/ clavulonate

25
Q

What is the First Line Treatment for Multi Drug Resistant Enterococci?

A

Linezolid
Daptomycin
Tigecycline

26
Q

What is the First Line Treatment for Multi Drug Resistant G- Bacteria

A

Carbapenem (imipenem or meropenem)

Polymyxin B , Tigecycline if Resistant to Carbapenem

Microbial Pharmacology (13 decks)

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