Anti-protozoal Flashcards
1
Q
Toxoplasma
A
Pyrimethamine + sulfadiazine
2
Q
Sleeping sickness (trypanosoma brucei)
A
Suramin and melarsoprol
3
Q
Chagas disease (trypanosoma cruzi)
A
Nifurtimox
4
Q
Leishmaniasis
A
Sodium stibogluconate
5
Q
Chloroquine
A
Blocks detoxification of heme into hemozoin, accumulation of heme is toxic to plasmodia…not useful for falciparum due to membrane pump resistance…causes retinopathy and pruritis
6
Q
Plasmodium falciparum
A
Artemether/lumefantine or atovaquone/proguanil
7
Q
Life-threatening malaria
A
Quinidine/quinine
8
Q
Anti-helminth agents
A
All immobilize helminths: albendazole, mebendazole, ivermectin, pyrantel, praziquantel, diethylcarbamazine