Anti-protozoal Flashcards

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1
Q

Toxoplasma

A

Pyrimethamine + sulfadiazine

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2
Q

Sleeping sickness (trypanosoma brucei)

A

Suramin and melarsoprol

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3
Q

Chagas disease (trypanosoma cruzi)

A

Nifurtimox

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4
Q

Leishmaniasis

A

Sodium stibogluconate

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5
Q

Chloroquine

A

Blocks detoxification of heme into hemozoin, accumulation of heme is toxic to plasmodia…not useful for falciparum due to membrane pump resistance…causes retinopathy and pruritis

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6
Q

Plasmodium falciparum

A

Artemether/lumefantine or atovaquone/proguanil

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7
Q

Life-threatening malaria

A

Quinidine/quinine

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8
Q

Anti-helminth agents

A

All immobilize helminths: albendazole, mebendazole, ivermectin, pyrantel, praziquantel, diethylcarbamazine

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