Anti-Infectives: Introduction Flashcards
what is a chemical substance originating from various species of microorganisms (bacteria, fungus, actinomyces) that suppresses growth or destroys other microorganisms
antibiotics
what do you consider with route of delivery for antibiotics?
highest ocular concentration is delivered locally
what do you consider with dosing of antibiotics?
weight, height, organ function (kidney & liver), therapeutic drug levels
what are the most common allergies to antibiotics?
penicillins & sulfa drugs
do you use antibiotics when there is mucopurulent discharge, no discharge, or putrid smelling discharge?
mucopurulent
do you use antibiotics when there is diffuse conjunctival injection or sectoral conjunctival injection?
diffuse conjunctival injection
do you use antibiotics when the cornea is compromised?
yes
do G+ or G- secrete unique antigenic nonenzymatic heat sensitive protein exotoxins?
both
does G+ or G- release pyretic, heat stable, mildly antigenic endotoxin (LPS) upon lysis?
G-
reaction to endotoxins can lead to?
anaphylactic shock & death
what is the most common nosocomial infection? is it G+ or G-? what is it called when it is more virulent?
staphylococcus aureus → G+
more virulent → MRSA
staphylococcus epidermis is G+ or G-? what is it called when it is more abundant?
G+
more abundant → MRSE
what cocci can cause corneal ulcers & pediatric conjunctivitis? is it G+ or G-?
streptococcus pneumoniae → G+
what cocci is intestinal & has some virulent strains & what is it called? is it G+ or G-?
enterococcus → G+
virulent strains → vancomycin resistent enterococcus (VRE)
what rod can cause post-LASIK keratitis? is it G+ or G-?
nocardia asteroides → G+
