Anti-Infective Drugs Flashcards
Are Viral or Bacterial Infections more contagious?
Viral.
Gram Negative Common Bacteria
E-coli Klebsiella Pseudomonas Salmonella HIB Cholera Syphillus Gonhorrhea Nisseria M
Gram Pos. Common Bacteria
Staphylococci Streptococci Enterococci Listeria C-Diff
Gram Pos Features
Membrane and peptidoglycan
Gram Neg Features
Membrane, Peptidoglycan and an extra outer membrane
Streptococcus Pyogenes
Pharyngitis:
Fever
Post Strep Disease: Glomerulonephritis
endocarditis
Can cause NF, meningitis. pneumonia, septic arthritis
Treatment choice is Pennicillin G
Clavulanic Acid and Tazobactam
B-lactamase inhibitors Combined into: Amoxicillan Ticarcillin Pip-taz (broad spectrum penicillin)
Cephalosporins
Largest antibiotic class -bactericidal -gram pos and neg. -1st choice for skin infec. Higher generations cross teh BBB
Carbapenems
IV only
Bactericidal
Broad spectrum
(meningitis, aspiration pneumonia)
Bacitracin
Polysporin
-Gram pos
Broad spec
topical prophylactic
Glycopeptide: Vancomycin
Used for MRSA, secondary treatment for C diff
Tetracyclines
Broad Spec
Gram pos and neg
Bacteriostatic
Treats for:
lyme disease, cholera, H-pylor, chlamydia, acne. malaria prophylactically.
SE: bone deformities
Macrolides
-Mycin suffix Bacteriocidal or static Gram pos mostly treatment for gonorrhea ex. erythromycin
Aminoglycosides
Gram neg
Treatment for conjuctivitis
ex. gentamycin
SE: nephro/neuro/hepatotoxicity
Lincosamides: Clindamycin
For serious Gi infections
Skin infections and surgical prophylaxis.
Fluororquinolones
-xacin suffix
gram neg mostly
for GI infections and UTIs
ex. ciprofloxacin
Metronidazole (Flagyl)
Inhibits DNA Synthesis, anti protozoal
treats C diff and H pylori
prophylactic for dental procedures
Sulfonamides
-sulfa
gram neg and pos
treats UTIs
Polyene Fungal Antibiotics
treats fungal infec.
increases cell membrane permeability
ex. Amphotericin, Nystatin (candida tx)
Rifampin
Treats TB, combined with 4 other meds
