Anti-Infective Drugs

Question 1

Are Viral or Bacterial Infections more contagious?

Answer 1

Viral.

Question 2

Gram Negative Common Bacteria

Answer 2

E-coli
Klebsiella
Pseudomonas
Salmonella
HIB
Cholera
Syphillus
Gonhorrhea
Nisseria M

Question 3

Gram Pos. Common Bacteria

Answer 3

Staphylococci
Streptococci
Enterococci
Listeria
C-Diff

Question 4

Gram Pos Features

Answer 4

Membrane and peptidoglycan

Question 5

Gram Neg Features

Answer 5

Membrane, Peptidoglycan and an extra outer membrane

Question 6

Streptococcus Pyogenes

Answer 6

Pharyngitis:
Fever
Post Strep Disease: Glomerulonephritis
endocarditis

Can cause NF, meningitis. pneumonia, septic arthritis

Treatment choice is Pennicillin G

Question 7

Clavulanic Acid and Tazobactam

Answer 7

B-lactamase inhibitors
Combined into: 
Amoxicillan
Ticarcillin
Pip-taz (broad spectrum penicillin)

Question 8

Cephalosporins

Answer 8

Largest antibiotic class
-bactericidal
-gram pos and neg. 
-1st choice for skin infec. 
Higher generations cross teh BBB

Question 9

Carbapenems

Answer 9

IV only
Bactericidal
Broad spectrum
(meningitis, aspiration pneumonia)

Question 10

Bacitracin

Answer 10

Polysporin
-Gram pos
Broad spec
topical prophylactic

Question 11

Glycopeptide: Vancomycin

Answer 11

Used for MRSA, secondary treatment for C diff

Question 12

Tetracyclines

Answer 12

Broad Spec
Gram pos and neg
Bacteriostatic

Treats for:
lyme disease, cholera, H-pylor, chlamydia, acne. malaria prophylactically.

SE: bone deformities

Question 13

Macrolides

Answer 13

-Mycin suffix
Bacteriocidal or static
Gram pos mostly 
treatment for gonorrhea
ex. erythromycin

Question 14

Aminoglycosides

Answer 14

Gram neg
Treatment for conjuctivitis
ex. gentamycin
SE: nephro/neuro/hepatotoxicity

Question 15

Lincosamides: Clindamycin

Answer 15

For serious Gi infections

Skin infections and surgical prophylaxis.

Question 16

Fluororquinolones

Answer 16

-xacin suffix
gram neg mostly
for GI infections and UTIs
ex. ciprofloxacin

Question 17

Metronidazole (Flagyl)

Answer 17

Inhibits DNA Synthesis, anti protozoal
treats C diff and H pylori
prophylactic for dental procedures

Question 18

Sulfonamides

Answer 18

-sulfa
gram neg and pos
treats UTIs

Question 19

Polyene Fungal Antibiotics

Answer 19

treats fungal infec.
increases cell membrane permeability

ex. Amphotericin, Nystatin (candida tx)

Question 20

Rifampin

Answer 20

Treats TB, combined with 4 other meds