Anti-histamine and Anti-emetics Flashcards
First generation antihistamines
antihistamines that cause a sedative side effect
Second generation antihistamines
More expensive and have been linked to heart problems, but do not have a sedative effect
Anti histamine - action
Inhibits the effects of histamine by antaganising the histamine receptors
First generation antihistamines - Chlopheniramine - example
Pirton
First generation antihistamines - Chlopheniramine - action
Binds to H1 receptor to prevent binding of histamine
Excreted in urine
First generation antihistamines - Chlopheniramine - uses
Allergies Anaphylactic reactions (after steroids and adrenaline) Mild anxiety in dogs and cats
First generation antihistamines - Chlopheniramine - side effects
Sedation
May reduce the seizure threshold
First generation antihistamines - Cyproheptadine - examples
Periactin
First generation antihistamines - Cyproheptadine - action
binds to H1 receptors and serotonin receptions to block acetycholine
First generation antihistamines - Cyproheptadine - uses
Allergic skin conditions
Appetite stimulant
First generation antihistamines - Cyproheptadine - side effects
Sedation
polyphagia
weight gain
may reduce seizure threshold
First generation antihistamines - Diphenhydramine - examples
Benadryl
First generation antihistamines - Diphenhydramine - action
binds to H1 receptors
excreted in the urine
First generation antihistamines - Diphenhydramine - uses
pruritus prevention of motion sickness allergic rhinitis in birds ferrets prior to vaccines if previous reaction Mild sedative
First generation antihistamines - Diphenhydramine - side effects
sedation
paradoxical excitement in cats
Liquid is unpleasant