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Farmacologie > Anthelmintica > Flashcards

Anthelmintica Flashcards

1
Q

Levamisole

A

nicotine agonist (nematocide)
stimuleert nicotine receptor -> spastische paralyse
adulte maagdarmnematoden en adulte longwormen
NIET paardennematoden

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2
Q

Pyrantel

A

nicotine agonist (nematocide)
stimuleert nicotine receptor -> spastische paralyse
adulte maagdarmnematoden
betere selectiviteit dan levamisole
wel bij paard

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3
Q

Fenbendazole

A

benzimidazoles
inhiberen microtubuli synthese
larvaire stadia en cestoden

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4
Q

Oxfendazole

A

benzimidazoles
inhiberen microtubuli synthese
larvaire stadie en cestoden

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5
Q

Albendazole

A

benzimidazoles
inhiberen microtubuli synthese
nematoden adult, larvair en ovocied
trematoden en cestoden

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6
Q

Mebendazole

A

benzimidazoles
inhiberen microtubuli synthese
cestoden

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7
Q

Flubendazole

A

benzimidazoles
inhiberen microtubuli synthese
cestoden

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8
Q

Triclabendazoles

A

benzimidazoles
inhiberen microtubuli synthese
enkel trematoden

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9
Q

Febantel

A

pro-benzimidazoles
inhiberen microtubuli synthese
KHD en vogels
metabolisatie tot fen- en oxfenbendazole thv lever

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10
Q

Netobimine

A

pro-benzimidazoles
inhiberen microtubuli synthese
metabolisatie tot albendazole

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11
Q

Ivermectine

A

ML
glutamaatkanalen en GABA stimuleren -> slappe paralyse
P-gp substraat
niet parenteraal bij paard
KHD en GHD

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12
Q

Eprinomectine

A

ML
glutamaatkanalen en GABA stimuleren -> slappe paralyse
lacterende herkauwers

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13
Q

Doramectine

A

ML
glutamaatkanalen en GABA stimuleren -> slappe paralyse
GHD
P-gp substraat
langste remanente werking

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14
Q

Selamectine

A

ML
glutamaatkanalen en GABA stimuleren -> slappe paralyse
KHD
ook vlooien en teken

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15
Q

Moxidectine

A

ML
glutamaatkanalen en GABA stimuleren -> slappe paralyse
KHD en GHD
niet bij veulens

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16
Q

Milbemycine oxime

A

ML
glutamaatkanalen en GABA stimuleren -> slappe paralyse
KHD

17
Q

Emodepside

A

nematocide
hond en kat in combo met praziquantel
agonist Iathrophiline-R -> inhibatoire NT -> Nicotine-R bezetten -> slappe paralyse
selectief
P-gp substraat

18
Q

Monepantel

A

nematocide
agonist van MPTL-1 R
selectief

19
Q

Derquantel

A

nematocide
in combi met abamectine (ML)
antagonist acetylcholine-R parasiet -> slappe paralyse

Farmacologie (12 decks)

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