Antenatal and Earl Pregnancy Flashcards
When can you do a combined antenatal screen?
11-13+6 weeks
When can you do a quadruple screen?
15-20 (16 weeks)
What consists of a combined antenatal screen?
- Free B-HCG, 2. NT & 3. PAPP-a
What does the combined and quadruple antenatal screen, screen for?
Downs, Edward’s, Palau
Patau is what trisomy?
13
Edward’s is what trisomy?
18
Down’s syndrome is what trisomy?
21
Quadruple antenatal screen consists of?
- HCG, 2. Inhibin A, 3. Alpha foetoprotein, 4. Unconjugated oestriol
When is foetal alpha protein raised?
Neural tube defects
What is amniocentesis
Procedure where a fine needle is used to aspirate amniotic fluid from the uterus and tested for definitive diagnosis of trisomy’s
What is chorionic villus sampling?
Fine needle sampling either transcervically or transabdominally whereby placental tissue is collected
What are risks of amniocentesis and chorionic villus sampling?
1 in 100 miscarriage
Increased HCG, thickened NT and decreased papp-a is suggestive of what trisomy?
Downs
Decreased HCG, foetal alpha protein, decreased oestriol BUT normal inhibin A is suggestive of?
Edward’s
Decreased alpha, oestriol and increased hCG & inhibin is suggestive of?
Downs