ANS part 2 Flashcards
length efferent fibers parasympathetic vs sympathetic
paraysympathetic preganglionic long post ganglionic short sympathetic preganglionc short post ganglionic long
types of innervation parasympathetic vs sympathetic
parasympathetic- discrete symapthetic- diffuse
neurotransmitters parasympathetic vs sympathetic
parasympathetic ganglia- acetycholine neuroeffector junctions- acetylcholine sympathetic ganglia- acetycholine neuroeffector junctions- norepinephrine (except sweat glands, vasodilators in skeletal muscle and adrenal medulla)
receptors parasympathetic vs sympathetic
parasympathetic ganglia- nicotinic cholinergic neuroeffector junecionts- muscarinic cholinergic sympathetic ganglia- nicotina cholinergic neuroeffector junctions- adrenergic
effector organ responess
- response post ganglionic release transmitter can be excitatory or inhibitory; response is tissue specific - in most organ systems both divisions (symp and parasympathetic) exert tonic action holding effectors in state of intermediate activity
post junctional excitation
- leads to increased force and/or frequency of muscle contraction, increase secretion in glands
examples post junctional excitation
- sympathetic adrenergic innervation -> contraction vascular smooth muscle - parasympathetic cholinergic receptors stimulation contraction GI smooth muscle
post junctional inhibition
- post junctional inhibition, decreasing contraction, secretion ect.
examples post junctional inhibition
- parasympathetic cholinergic innervation -> decreased freqnecy of contraction of cardiac muscles - sympathetic adrenergic innervation -> relaxation GI smooth muscle
parasympathetic nervous system effects
- discrete and selective - important for vegetative functions and maintenance of status quo, acts to conserve and restore energy; rest and digest - its innervation to some organs is essential for life
parasympathetic nervous system dual innervation predominant tone
parasympathetic
parasympathetic nervous system examples of responses
- decrease heart rate - decrease blood pressure - increase GI motility and secretions - increase absorption or nutrients - increase excretory functions - increase salivary section - constriction of bronchioles - miosis
sympathetic nervous system effects
- generally diffuse and nonselective system usually discharges as unit (some selectivity in organs like heart and blood vessels) - important for survival during stress (flight or flight)
body survival without SNS?
- body can survive w/o SNS but some protective functions will be lost
examples of responses from SNS
- increase heart rate - increase blood pressure - increase blood flow to skeletal muscle - decrease blood flow to skin and splanchnic bed - increase blood glucose - dilation of bronchioles - mydriasis
interactions between parasympathetic and sympathetic systems
- most organs have dual innervation - opposing effects - complementary effects - no interaction
what organ does NOT have dual innervation for parasympathetic and sympathetic NS
blood vessels which only receive sympathetic innervation
opposing effects interaction between paraysympathetic and sympathetic systems
- most common balanced antagonism (ex heart and bladder) - most system may heavily predominate (ex. in GI tract parasympathetic)
complementary effects interaction between parasympathetic and sympathetic systems
- ex. in salivary gland PNS stimualtes watery secretion and SNS stimulates viscous secretion - ex. in male genitalia PNS mediates errection SNS mediates ejaculation (point and shoot)
no interaction interaction between parasympathetic and sympathetic systems
- organ innervated selectively by one system (ex blood vessels)
Sites for drug action in ANS
- cerebral cortex (high CNS centers) - lower brain centers and medullary centers - autonomic afferents - autonomic eferents - effector organ
autonomic efferents drug action site ANS
-autonomic ganglia- not selectivity for symp or parasympathetic ganglia but more symp post gang gibers than parasympathetic fibers so predominant response to stimulation at ganglia = sympathetic - neuroeffector junction