ANS Drugs Flashcards

0
Q

Solifenacin

A

Tertiary Amine With high CNS penetrance

- Urinary incontinence

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1
Q

Darifenacin

A

Tertiary amine With high CNS penetrance

- urinary incontinence

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2
Q

Oxybutynin

A

Tertiary amine with low CNS penetrance

- Indicated in urinary incontinence

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3
Q

Tolterodine

A

Tertiary amine with low CNS penetrance

- Indicated in urinary incontinence

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4
Q

Trospium

A

Quaternary amine

- Indicated in urinary incontinence

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5
Q

Ipratropium

A

Quaternary amine

- Indicated in urinary incontinence

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6
Q

Tiotropium

A

Quaternary amine

- Indicated in urinary incontinence

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7
Q

Donepezil

A

Central acetylcholinesterase inhibitor

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8
Q

Revastamine

A

Central acetylcholinesterase inhibitor

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9
Q

Galantamine

A

Central acetylcholinesterase inhibitor

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10
Q

Phenylephrine

A

Local Alpha-adrenergic agonist

Nasal decongestant

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11
Q

Oxymetazoline

A

Local alpha-adrenergic agonist

  • red eye (ophthalmic formulation)
  • longer acting nasal decongestant (afrin)
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12
Q

Tetrahydrozoline

A

Local alpha-adrenergic agonist

- red eye

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13
Q

Clonidine

A

Systemic alpha-adrenergic agonist

  • HTN (not first line)
  • ADHD
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14
Q

Tizanidine

A

Systemic alpha-adrenergic agonist

Muscle relaxant

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15
Q

Methyldopa

A

Systemic alpha-adrenergic agonist

- pregnant hypertensive

16
Q

Dexmedetomidine

A

Systemic alpha-adrenergic agonist

Surgical and ICU sedation

17
Q

Phenoxybenzamine

A

Nonselective Alpha antagonist

Preoperative pheochromocytoma management

18
Q

Phentolamine

A

Nonselective Alpha antagonist

Preoperative pheochromocytoma management

19
Q

Propranolol

A

Nonselective beta antagonist

Contraindicated in asthma and heart failure

20
Q

Timolol

A

Nonselective beta antagonist

21
Q

Nadolol

A

Nonselective beta antagonist

22
Q

Acebutelol

A

Partial Beta Antagonist/ direct sympathomimetic

23
Q

Pindolol

A

Partial Beta antagonist/ sympathomimetic

24
Q

Isoproterenol

A

Non specific Beta-adrenergic agonist

  • Bronchdilation
  • tachycardia/arrythmias (contraindicated in heart issues)
25
Q

Dobutamine

A

Beta-adrenergic agonist

26
Q

Terazosin

A

Alpha-1 antagonist

27
Q

Doxazosin

A

Alpha-1 Antagonist

28
Q

Prazosin

A

Alpha-1 Antagonist

29
Q

Methacholine

A

Direct muscarinic agonist

30
Q

Carbachol

A

Direct muscarinic agonist

31
Q

Bethachol

A

Direct muscarinic agonist

32
Q

Cevimaline

A

Direct muscarinic agonist

- Greatest affinity for the M3 receptor

33
Q

Atropine

A

Nonspecific muscarinic antagonist

34
Q

Scopolamine

A

Nonspecific muscarinic antagonist

- Antiemetc

35
Q

Hyocyamine and dicyclomine

A

Nonselective muscarinic antagonists

36
Q

Benzotropine and trihexaphenadyl

A

M1 Selective muscarinic antagonist

  • tertiary amine
  • M1 selective : (park the Benz so you can drive the Beamer)
37
Q

All adrenergic antagonists nomenclature

A

All are LOLs or SINS

- except for non selective alpha antagonist