Aneurysms and carotid artery surgery Flashcards

1
Q

When does a dilatation of the aorta become classified as an aneurysm?

A

When it dilates to an increase of > 50% (normal diameter of the aorta = 2cm)

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2
Q

Where are the majority of aneurysms found?

A

95% are infrarenal abdominal aneurysms - Located in the part of the abdominal aorta below the kidneys

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3
Q

Whats the difference between true and false aneurysms?

A

True - disease affects all 3 layers of the aorta wall

False - usually only affects outer layer, usually caused by trauma

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4
Q

What can cause aneurysms?

A

Degenerative disease
Connective tissue disease
Infection (mycotic aneurysm)
Trauma

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5
Q

What are the risk factors for aneurysms?

A
Male
Age
Smoking
Hypertension
Family History
Genetics
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6
Q

How can asymptomatic aneurysms be found?

A

Clinical exam - pulsatile mass (false a etc)
After family member diagnosis
Screening - all males over 65yo get US
Incidentally in a scan for something else

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7
Q

What is the criteria for a successful screening regime?

A
Definable disease
Prevalence
Severity of disease
Natural history is understood
Reliable detection 
Early detection confers advantage
Treatment options available 
Cost effective
Feasibility
Deemed acceptable - complaincy
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8
Q

What classifies as a small aneurysm?

A

3-4.4cm

Annual USS scans

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9
Q

What classifies as a medium aneurysm?

A

4.5-5.5cm

3 monthly USS scans

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10
Q

What classifies as a large aneurysm?

A

> 5.5cm

Immediately referred to vascular surgeon

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11
Q

What are some unusual presentations of aneurysms?

A
Distal embolisation
Aortocaval fistula
Aortoenteric fistula (connection between aorta and intestines/stomach/oesophagus) 
Ureteric occlusion
Duodenal obstruction
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12
Q

How do we assess patient fitness for aneurysm surgery?

A
Full history and exam - comorbidity, function
Full blood tests
ECG
ECHO
Pulmonary function tests
Myocardial perfusion scans
Cardio-pulmonary exercise testing
End of the bed test?
Patient preference
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13
Q

What are some pros of cranial ultrasound?

A

No radiation
No contrast - safe in renal failure
Cheap

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14
Q

What are some cons of cranial ultrasound

A

Operator dependent

Inadequate for surgical planning

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15
Q

What are some pros of CTA and MRA when planning surgery?

A

Quick

Not operator dependent

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16
Q

What are some cons of CTA or MRA for planning surgery?

A

Contrast used

Radiation

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17
Q

What is done to assess aneurysm before surgery?

A

Ultrasound
Computed tomography angiography
Magnetic resonance angiography

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18
Q

What procedure involves making a large incision in the abdomen to expose the aorta and aneurysm sac?

A

Laparotomy - from xiphisternum to pubic symphysis

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19
Q

What are some complications of open surgery on aneurysms?

A
General anaesthetic use
Big operation - healing time, infection
Incisional hernia
Damage to nearby anatomy
Risk of preoperative MI
Renal failure
Colonic ischaemia
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20
Q

Describe endovascular repair (EVAR) of aneurysms

A

Small incision in groin, where special instruments are inserted through a catheter in the femoral arteries to thread them up to the aneurysm. At aneurysm, surgeon places stent and graft to support aneurysm.

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21
Q

What are some complications of EVAR?

A
Damage to veins/arteries/nerves on insertion
Rupture of aneurysm 
Endoleak
Femoral artery dissection/pseudoaneurysm
Distal emboli/ischaemia
22
Q

What could surgery on aneurysms lead to clinically?

A

DVT/PE
MI
Stroke
Death

23
Q

What are some general complications following both EVAR and open surgery?

A
Wound infection
Bleeding
Pain
Scarring
(Radiation/contrast if used)
24
Q

What are endoleaks?

A

Blood leaks back into aneurysm sac following EVAR, 5 types:
I - gap between graft and vessel at seal
II- increased pressure forces blood out
III- defect or misalignment of endograft
IV - porosity of graft
V- permeability of graft allows transmission of pressure into sac

25
What is a type I endoleak?
I - gap between graft and vessel at seal, requires urgent attention
26
What is a type II endoleak?
II- increased pressure forces blood out MOST COMMON
27
What is a type III endoleak?
III- defect or misalignment of endograft, requires urgent attention
28
What is a type IV endoleak?
IV - porosity of graft, occurs soon after procedure
29
What is a type V endoleak?
V- permeability of graft allows transmission of pressure into sac ENDOTENSION, controversial
30
What is there a risk of in EVAR?
Incomplete removal of blood can lead to Abdominal compartment syndrome
31
Why must you prep abdomen before surgery?
Acts as a tamponade normally, which is lost following anaesthetics
32
What is atherosclerosis of the carotid arteries associated with clinically?
Transient ischaemic attacks | Stroke
33
What can cause cerebral infarctions?
``` AF Carotid atheromatous plaque rupture Endocarditis MI Carotid artery injury/dissection Drug abuse Haematological disorders e.g. sickle cell Primary intracerebral haemorrhage ```
34
What % of strokes are due to ischaemia?
84%
35
What % of strokes are due to haemorrhage?
16% (primary intracerebral +subarachnoid haemorrhages)
36
What is Virchows triad?
Three broad range of factors associated with thrombosis: Hypercoagulability Haemodynamic changes - stasis, turbulence Endothelial damage/dysfunction
37
What are some risk factors for carotid artery atherosclerosis?
``` Smoking Diabetes Hypertension Family history Male sex Previous DVT Hyperlipidaemia Hypercholesterolaemia Obesity Age ```
38
How can we diagnose stroke?
History and examination CT Carotid USS - measure flow and direction
39
What is poiseuilles law?
Flow depends on resistance and radius of the vessels As radius decreases, velocity increases
40
What therapy is suggested to those with carotids artery atherosclerosis?
``` Smoking cessation Control of hypertension Antiplatelet agents e.g. aspirin, clopidogrel Statins Diabetic control ``` If severe: Carotid endarterectomy Stenting
41
What is the circle of willis?
circulatory anastomosis that supplies blood to the brain and surrounding structures.
42
Describe Carotid endarterectomy
clamp above and below diseased section, remove plaque and repair artery to create open channel
43
What is the general rule with superficial and deep vessels?
Superficial - continue following bifurcation | Deep - end and supply area
44
What are some complications of Carotid endarterectomy ?
``` Wound infection Bleeding Scarring Anaesthetic risks Nerve damage ```
45
What are the nearby nerves that can be damaged during Carotid endarterectomy, and how would damage present?
Vagus nerve - PS control of lungs, GI tract Hypoglosseal nerve - numb lips and tongue Glossopharyngeal nerve - loss of voice
46
What is the hypoglosseal nerve responsible for?
Lip and tongue innervation
47
What is vagus nerve responsible for?
Parasympathetic control of hearts, lung, GI tract etc
48
What is the glossopharyngeal nerve responsible for?
Voice
49
What are some possible complications of Carotid endarterectomy?
Plaque rupture Hypoperfusion Clotting
50
When should surgery be considered?
Symptomatic but 50-69% stenosis | Asymptomatic but >70% stenosis