Anestheisa Pharm Test 1 Part 4

Question 1

which induction agents are best for cardiac patients

Answer 1

etomidate and benzos

Question 2

anesthetics that cause bronchodilation

Answer 2

propofol and ketamine

Question 3

induction dose of midazolam

Answer 3

0.1-0.3 mg/kg

Question 4

induction dose of diazepam

Answer 4

0.3-0.6 mg/kg

Question 5

induction dose of lorazepam

Answer 5

0.03 - 0.1 mg/kg

Question 6

protein binding of the benzos: midazolam: diazepam: lorazepam:

Answer 6

94%; 98%; 98%

Question 7

1/2 life of midazolam

Answer 7

1-4 hours

Question 8

1/2 life of diazepam

Answer 8

30-50hrs

Question 9

1/2 life of lorazepam

Answer 9

12hrs

Question 10

duration of action of midazolam

Answer 10

15-20 min

Question 11

duration of action of diazepam

Answer 11

15-30 min

Question 12

duration of action of lorazepam

Answer 12

60-120 min

Question 13

__________________ was THE induction agent prior to propofol

Answer 13

thiopental

Question 14

T/F: it is okay to give your patient a pre-sedative dose of versed and leave them unattended to go ensure the OR is set up

Answer 14

FALSE

Question 15

____________________ has the greatest selectivity for GABA-A receptor, and interacts the least with other receptors

Answer 15

etomidate

Question 16

what should be on the label when preparing a propofol syringe

Answer 16

1. initials 2. date 3. time of expiration

Question 17

what component of propofol can cause increased bronchial tone leading to bronchoconstriction

Answer 17

metabisulfite preservatives

Question 18

when mixing lidocaine with propofol, no more than ___________mL of lido with ________ mL of prop

Answer 18

20; 20

Question 19

when mixing propofol and lidocaine, the medications start to separate in the syringe after _______________

Answer 19

1 hr

Question 20

GABA-A receptors is ______________ gated

Answer 20

ligand

Question 21

NMDA receptors is ________________ gated

Answer 21

ligand

Question 22

sx of PRIS

Answer 22

1. hypertriglyceridemia 2. metabolic acidosis 3. rhabdomyolysis 4. renal failure 5. HD instability

Question 23

active metabolites of benzo metabolism can prolong duration in patients with ______________________

Answer 23

renal failure

Question 24

which meds also have an agonistic (increase) effect on 5HT receptors

Answer 24

BZ and ketamine

Question 25

which meds also have an antagonistic effect on 5HT (decrease) Receptors

Answer 25

thiopental and propofol

Question 26

which meds also antagonize NMDA receptors

Answer 26

propofol ketamine precedex

Question 27

which meds agonize glycine receptors

Answer 27

BZ, etomidate, and propofol

Question 28

which meds antagonize glycine

Answer 28

thiopental

Question 29

which meds antagonize AMPA receptors

Answer 29

thiopental, propofol, and BZ

Question 30

GABA stimulation can decrease _____________, ________________, and ____________

Answer 30

fear; anxiety; and convulsions

Question 31

1/2 life of propofol

Answer 31

40 min

Question 32

DOA of propofol

Answer 32

3-10 min

Question 33

1/2 life of etomidate

Answer 33

2.6 hours

Question 34

DOA of etomidate

Answer 34

3-12 min

Question 35

DOA of ketamine

Answer 35

5-15 min

Question 36

DOA of precedex

Answer 36

60-120 min