Anestheisa Pharm Test 1 Part 4 Flashcards
which induction agents are best for cardiac patients
etomidate and benzos
anesthetics that cause bronchodilation
propofol and ketamine
induction dose of midazolam
0.1-0.3 mg/kg
induction dose of diazepam
0.3-0.6 mg/kg
induction dose of lorazepam
0.03 - 0.1 mg/kg
protein binding of the benzos: midazolam: diazepam: lorazepam:
94%; 98%; 98%
1/2 life of midazolam
1-4 hours
1/2 life of diazepam
30-50hrs
1/2 life of lorazepam
12hrs
duration of action of midazolam
15-20 min
duration of action of diazepam
15-30 min
duration of action of lorazepam
60-120 min
__________________ was THE induction agent prior to propofol
thiopental
T/F: it is okay to give your patient a pre-sedative dose of versed and leave them unattended to go ensure the OR is set up
FALSE
____________________ has the greatest selectivity for GABA-A receptor, and interacts the least with other receptors
etomidate
what should be on the label when preparing a propofol syringe
- initials 2. date 3. time of expiration
what component of propofol can cause increased bronchial tone leading to bronchoconstriction
metabisulfite preservatives
when mixing lidocaine with propofol, no more than ___________mL of lido with ________ mL of prop
20; 20
when mixing propofol and lidocaine, the medications start to separate in the syringe after _______________
1 hr
GABA-A receptors is ______________ gated
ligand
NMDA receptors is ________________ gated
ligand
sx of PRIS
- hypertriglyceridemia 2. metabolic acidosis 3. rhabdomyolysis 4. renal failure 5. HD instability
active metabolites of benzo metabolism can prolong duration in patients with ______________________
renal failure
which meds also have an agonistic (increase) effect on 5HT receptors
BZ and ketamine
