anemia yale case study

Question 1

what lab to order to distinguish between iron def anemia and other possibilites

Answer 1

ferritin

Question 2

what is ferritin

Answer 2

primary iron storage protein in body

gold standard for dx of IDA

decreased in IDA

Question 3

tests for IDA to give more info about iron storse

Answer 3

iron
iron biding capacity
transferrin saturation

Question 4

what is trasnferrin

Answer 4

protein used to transport iron in the circulation

usually from spleen

increased in IDA

Question 5

total iron binding capacity

Answer 5

medical lab test that measures blood’s capacity to bind iron with transferrin

increased in IDA

Question 6

soluble transferrin receptor

Answer 6

serum component of iron binding receptor on cell membranes

elevated in IDA

Question 7

erythrocyte protoporphyrin

Answer 7

precursor to heme before iron is bound

increased in IDA

Question 8

causes of IDA

Answer 8

1. poor absorption of iron
2. iron loss
   3, inadequate iron intake, rare

r/t menses, GIB d/t ASA or NSAIDS, various cancers or abnormalities of gut (angiodysplasia, celiac disease, PUD, esophagitis, vascular ectasia)

Question 9

what is the recommendation for treatment of iron deficiency in absence of anemia in women are pregnant or trying to get pregnant

Answer 9

there is no recommendation for treatment for iron deficiency in absence of anemia

conservative approach would be prenantal, vitamin c, and encourage diet rich in high iron foods