Anemia I

Question 1

proteins on membrane of RBC

Answer 1

spectrin

actin

Question 2

increases RBC affinity for hemoglobin

Answer 2

decrease temp
decrease DPG
increase pH

Question 3

decreases RBC affinity for HB

Answer 3

increase temp
increase DPG
decrease PH

Question 4

two general ways to become anemic

Answer 4

decreased production

or increased destruction

Question 5

MCV equation

Answer 5

%HCT x 10/RBC

Question 6

MCH normal

Answer 6

27-34

Question 7

MCHC normal

Answer 7

32-37

Question 8

RDW normal

Answer 8

11.5-14.5

Question 9

normal reticulocyte count

Answer 9

1%

Question 10

increased RDW

Answer 10

ansiocytosis

increased variability in RBC size

Question 11

polychromasa

Answer 11

indicates a shift in marrow reticulocytes nto the periphery in response to increase stimulation (aka increased epo)

Question 12

you want to have increased reticulocytes when..

Answer 12

anemic

to show that your body is trying to compensate

Question 13

reticulocyte production index

Answer 13

tells you if the bone marrow is adequately compensating for the degree of anemia

Question 14

RPI equation

Answer 14

reticulocyte percentage x (HCT/normal HCT)/ maturation factor (days n marrow)

> 2: adequate response
<2: inadequate response

Question 15

maturation term def and normal

Answer 15

maturation time of RBCs in days at various levels of anemia

normal = 1