Anemia due to underproduction

Question 1

Anemia characterized by a low corrected reticulocyte count…

Answer 1

Anemia due to underproduction

Question 2

What can infect progenitor red cells causing a temporary stop to erythropoiesis, which leads to significant anemia in the setting of a preexisting marrow stress?

Answer 2

Parvovirus B19

Question 3

What anemia is caused by damage to hematopoietic stems cells?

Answer 3

Aplastic anemia

Question 4

What is seen on biopsy of a patient with aplastic anemia?

Answer 4

Empty, fatty marrow

Question 5

Pancytopenia and a low reticulocyte count are seen within the setting of aplastic anemia. What is the underlying cause of these findings?

Answer 5

Damage to hematopoietic stem cells

Question 6

What are the causes of aplastic anemia?

Answer 6

Drugs
Chemicals
Viral infections
Autoimmune damage

Question 7

How will immunosuppression help with some aplastic anemias?

Answer 7

Some idiopathic cases of aplastic anemia are due to abnormal T-cell activation with release of cytokines

Question 8

What is a myelophthisic process?

Answer 8

Pathological process involving the replacement of bone marrow causing hematopoiesis impairment and pancytopenia