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Hematology 1 > Anemia > Flashcards

Anemia Flashcards

1
Q

Ischemia vs Anemia

A

Ischemia - particular to one organ only

Anemia - systemic

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2
Q

Production of Erythroid precursors cells that are defective

A

Ineffective erythropoiesis ( Megaloblastic anemia)

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3
Q

Decrease in the number of erythroid precursors in the bone marrow

A

Insufficient anemia (Aplastic anemia)

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4
Q

Used to assess the Bone marrow response

A

Reticulocyte count

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5
Q

The formula for Absolute Reticulocyte Count

A

(Retic% x RBC count) / 100

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6
Q

The formula for corrected reticulocyte count

A

CRC= Retic% x (Patient HCT/45)

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7
Q

Ovalocytes are only seen in

A

Megaloblastic anemia

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8
Q

Other term for sickle cells

A

Drepanocytes/ Meniscocytes

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9
Q

Hb C crystal

A

Bar of Gold / Washington monument

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10
Q

Hb SC crystal

A

Finger shaped

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11
Q

Target cells

Common finding in microcytic anemia’s

A

Target cells

—> Hollow pallor ( does not contain hemoglobin)

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12
Q

Poikilocyte associated in Kidney disease

A

Burr cells

–> if normal: Ecchinocytes

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13
Q

Poikilocyte that is seen in overproliferation of cells in the BM

A

Teardrop cells / Dacryocytes

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14
Q

Feature / sign of recovery from anemias

A

Reticulocytes

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15
Q

Helpful in assessing early bone marrow response after treatment for anemia

A

Immature reticulocyte fraction

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16
Q

Electrolyte imbalances often result to this type of poikilocyte

A

Stomatocytes

17
Q

An iron binding protein in the granules of neutrophils. It’s affinity is greater than that of transferrin

A

Lactoferrin

18
Q

Type of anemia wherein there is sideropenia in the face of abundant iron stores

A

Anemia of Chronic Inflammation

19
Q

Type of anemia characterized by the prevention of the production of protoporphyrin or incorporation of iron into it

A

Sideroblastic anemia

20
Q

The hallmark for sideroblastic anemia

A

Ring sideroblasts

21
Q

Anemia characterized by accumulation of aminolevulinic acid (ALA), iron and protoporphyrin

A

Lead Poisoning

22
Q

RPI that signifies bone marrow failure

A

<2 RPI

23
Q

Most common drug and chemical associated with aplastic anemia

A

Drug: chloramphenicol
Chemical: benzene

24
Q

The selective and severe disease in erythrocytes precursors

A

Pure Red Cell Aplasia

25
Q

Congenital disease associated with Pure red cell aplasia

A

Diamond Blackfan Anemia

26
Q

Most common aplastic anemia

A

Fanconi’s anemia

27
Q

Common finding in pure red cell aplasia

A

Severe anemia and reticulocytopenia (decreased reticulocytes) with normal RBCs and Platelets

28
Q

Anemia that exhibits hypercellular BM but ineffective erythropoiesis

A

Congenital dyserythropoietic anemia

29
Q

Infiltration of abnormal cells into the BM and subsequent replacement of normal hematopoietic cells

A

Myelophthisic anemia

Hematology 1 (13 decks)

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