Anatomy of the Skin Flashcards
How many layers of the skin are there?
3
What are the three main layers of skin called?
-Epidermis
-Dermis
-Hypodermis
What is the epidermis mainly formed from?
Keratinocytes undergoing terminal maturation
What other cells occupy the epidermis?
-Melanocytes
-Langerhans cells
-Merkel cells
What are melanocytes responsible for?
The are responsible for melanin production and pigment formation
What are Langerhans cells?
Antigen-presenting dendritic cells
What are Merkel cells?
Sensory mechanoreceptors
What is the epidermis divided into?
Layers of keratinocytes
What are the different layers of the epidermis?
-Stratum basale
-Stratum spinosum
-Stratum granulosum
-Stratum lucidum
-Stratum corneum
Which layer of the epidermis is the deepest from the surface?
Stratum basale
What occurs in the Stratum basale layer of the epidermis?
Mitosis of keratinocytes
How are keratinocytes joined in the Stratum spinosum layer of the epidermis?
Joined by tight intercellular junctions called desmosomes
What occurs in the Stratum granulosum layer of the epidermis?
Cells secrete lipids and other waterproofing molecules
What occurs in the Stratum lucidum layer of the epidermis?
Cells lose nuclei and drastically increase keratin production
What occurs in the Stratum corneum layer of the epidermis?
Cells lose all organelles and continue to produce keratin