Anatomy of the Skin Flashcards

1
Q

How many layers of the skin are there?

A

3

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2
Q

What are the three main layers of skin called?

A

-Epidermis
-Dermis
-Hypodermis

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3
Q

What is the epidermis mainly formed from?

A

Keratinocytes undergoing terminal maturation

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4
Q

What other cells occupy the epidermis?

A

-Melanocytes
-Langerhans cells
-Merkel cells

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5
Q

What are melanocytes responsible for?

A

The are responsible for melanin production and pigment formation

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6
Q

What are Langerhans cells?

A

Antigen-presenting dendritic cells

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7
Q

What are Merkel cells?

A

Sensory mechanoreceptors

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8
Q

What is the epidermis divided into?

A

Layers of keratinocytes

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9
Q

What are the different layers of the epidermis?

A

-Stratum basale
-Stratum spinosum
-Stratum granulosum
-Stratum lucidum
-Stratum corneum

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10
Q

Which layer of the epidermis is the deepest from the surface?

A

Stratum basale

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11
Q

What occurs in the Stratum basale layer of the epidermis?

A

Mitosis of keratinocytes

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12
Q

How are keratinocytes joined in the Stratum spinosum layer of the epidermis?

A

Joined by tight intercellular junctions called desmosomes

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13
Q

What occurs in the Stratum granulosum layer of the epidermis?

A

Cells secrete lipids and other waterproofing molecules

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14
Q

What occurs in the Stratum lucidum layer of the epidermis?

A

Cells lose nuclei and drastically increase keratin production

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15
Q

What occurs in the Stratum corneum layer of the epidermis?

A

Cells lose all organelles and continue to produce keratin

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16
Q

How many days does a keratinocyte take to travel from the Stratum basale to the Stratum corneum?

A

30-40 days

17
Q

Where is the dermis found?

A

Right below the epidermis

18
Q

How many layers does the dermis have?

A

2

19
Q

What are the two layers of the dermis called?

A

-Papillary Layer
-Reticular Layer

20
Q

What function do the thicker bundles of collagen fibres have on the reticular layer of the dermis?

A

Provides durability

21
Q

What helps provide the reticular layer of the dermis durability?

A

Thicker bundles of collagen fibres

22
Q

What are some of the cell types and structures found in the dermis layer?

A

-Fibroblasts
-Mast cells
-Blood vessels and cutaneous sensory nerves
-Skin appendages

23
Q

What is the function of a fibroblast?

A

Cells which synthesis the extracellular matrix

24
Q

What are fibroblast composed of?

A

-Collagen
-Elastin

25
Q

What are mast cells?

A

Histamine granule-containing cells of the innate immune system

26
Q

What are some examples of skin appendages?

A

-Hair follicles
-Nails
-Sebaceous and sweat glands

27
Q

What do hair follicles and sebaceous glands combine to form?

A

Pilosebaceous Unit

28
Q

Where is the hypodermis layer found?

A

Immediately below the dermis layer

29
Q

What is found in the hypodermis layer?

A

Adipose tissue

30
Q

What is another word for adipose tissue?

A

Body fat

31
Q

What are all the functions of the skin?

7

A

-Defence against infections and infestations
-Protection against irritants, ultraviolet irradiation and injury
-Controlling water and heat loss
-Important sensory organ which distinguishes pain, touch, itching, vibrations, heat and cold
-Maintain body temperature
-Vitamin D is also synthesised in the skin
-Important organ of social communication and sexual contact.