Anatomy and Physiology Flashcards
Morphologic characteristics of RBC?
- Biconcave in shape
- Live about 100-120 days (destroyed in the spleen)
Function of RBC?
carry oxygen
A drop in normal blood oxygen concentration trigger formation of what?
Erythropoietin
Morphologic characteristics of Neutrophils?
Fine pinkish granules, lobed nucleus (2-5 parts)
Function of Neutrophils?
phagocytosis (smaller particles)
Morphologic characteristics of lymphocytes?
Agranulocytes, smaller cells with large nucleus, thin layer cytoplasm.
The function of lymphocytes?
Immunity (B-cells and T- Cells)
- Can move in and out of lymphatic circulatory system
Morphologic characteristics of monocytes?
Larger cells in the body, vary nuclei shape
The function of monocytes?
Phagocytes (larger particles)
Morphologic characteristics of Eosinophils?
Coarse reddish granules, bi-lobed nucleus
The function of Eosinophils?
Allergic reaction, parasitic infections (worms), controls inflammation
Morphologic characteristics of basophils?
Deep blue-stained granules, bi-lobed nucleus
The function of basophils?
Release histamine, anticoagulation, and heparin
What is vascular spasm?
Initial rxn to damage of the blood vessel (vasoconstriction)
What are vascular spasms triggered by?
- Vascular smooth muscle injury, chemicals from endothelial cells and platelets, and local pain receptor reflexes.
- Most effective in small vessels and vessels that are transected
What is platelet plug formation?
When a platelet aggregation forms a temporary plug
Role of the Von Willebrand factor in platelet plug formation?
It stabilizes bound platelets, it forms a bridge between collagen and platelets.
What do platelets form to become stickier?
Pseudopods
What is ADPs role in platelet plug formation?
ADP causes additional platelets to stick in the area and release their contents
What does the white pulp of the spleen consist of?
Lymphatic tissue (mostly B-cell lymphocytes) arranged around central arteries
The function of the white pulp?
Immunity; B-cell proliferation into antibody-producing plasma cells
What does the red pulp of the spleen consist of?
- Venous sinuses filled with blood and thin plates of tissue (splenic cords)
- Splenic cords consist of red blood cells, macrophages, lymphocytes, plasma cells, and granulocytes
What is the function of the red pulp?
Phagocytosis of bacteria and worn-out or damaged red blood cells and platelets
