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Hematology Oncology > Anatomy and Physiology > Flashcards

Anatomy and Physiology Flashcards

1
Q

Morphologic characteristics of RBC?

A
  • Biconcave in shape

- Live about 100-120 days (destroyed in the spleen)

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2
Q

Function of RBC?

A

carry oxygen

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3
Q

A drop in normal blood oxygen concentration trigger formation of what?

A

Erythropoietin

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4
Q

Morphologic characteristics of Neutrophils?

A

Fine pinkish granules, lobed nucleus (2-5 parts)

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5
Q

Function of Neutrophils?

A

phagocytosis (smaller particles)

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6
Q

Morphologic characteristics of lymphocytes?

A

Agranulocytes, smaller cells with large nucleus, thin layer cytoplasm.

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7
Q

The function of lymphocytes?

A

Immunity (B-cells and T- Cells)

- Can move in and out of lymphatic circulatory system

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8
Q

Morphologic characteristics of monocytes?

A

Larger cells in the body, vary nuclei shape

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9
Q

The function of monocytes?

A

Phagocytes (larger particles)

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10
Q

Morphologic characteristics of Eosinophils?

A

Coarse reddish granules, bi-lobed nucleus

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11
Q

The function of Eosinophils?

A

Allergic reaction, parasitic infections (worms), controls inflammation

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12
Q

Morphologic characteristics of basophils?

A

Deep blue-stained granules, bi-lobed nucleus

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13
Q

The function of basophils?

A

Release histamine, anticoagulation, and heparin

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14
Q

What is vascular spasm?

A

Initial rxn to damage of the blood vessel (vasoconstriction)

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15
Q

What are vascular spasms triggered by?

A
  • Vascular smooth muscle injury, chemicals from endothelial cells and platelets, and local pain receptor reflexes.
  • Most effective in small vessels and vessels that are transected
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16
Q

What is platelet plug formation?

A

When a platelet aggregation forms a temporary plug

17
Q

Role of the Von Willebrand factor in platelet plug formation?

A

It stabilizes bound platelets, it forms a bridge between collagen and platelets.

18
Q

What do platelets form to become stickier?

A

Pseudopods

19
Q

What is ADPs role in platelet plug formation?

A

ADP causes additional platelets to stick in the area and release their contents

20
Q

What does the white pulp of the spleen consist of?

A

Lymphatic tissue (mostly B-cell lymphocytes) arranged around central arteries

21
Q

The function of the white pulp?

A

Immunity; B-cell proliferation into antibody-producing plasma cells

22
Q

What does the red pulp of the spleen consist of?

A
  • Venous sinuses filled with blood and thin plates of tissue (splenic cords)
  • Splenic cords consist of red blood cells, macrophages, lymphocytes, plasma cells, and granulocytes
23
Q

What is the function of the red pulp?

A

Phagocytosis of bacteria and worn-out or damaged red blood cells and platelets

Hematology Oncology (9 decks)

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