Anatomy 2 Open ended final exam Flashcards
Functions of the kidneys is to regulate
- ionic composition
- blood osmolarity
- blood volume
- blood pressure
- blood pH
2 types of nephrons
- cortical - most abundant 80%, produce urine, 2nd capillary bed: peritubular capillaries
- juxtamedullary - to maintain the contraction in the renal medulla, 2nd capillary bed: vasa reda
3 types of transport of material between nephron and blood
- glomerular filtration - non selective movement of material from the blood into the bowman’s capsule due to hydrostatic pressure
- tubular reabsorption - in general a selective transport of material from the nephron to the blood due to osmotic pressure
- tubular secretion - selective transport of material moving from the blood into the nephron done by transport proteins
filtration membrane consists of
- glomerular endothelium - filters out the red blood cells
- basal lamina - filters out the large proteins
- filtration slits between podocytes - filters out medium proteins
rules of the kidneys
- wherever Na+ goes Cl- goes
- wherever Na+ goes (H2O) water goes
- wherever Na+ goes K+ goes in the opposite direction
micturition reflex
- stretch receptors in the bladder signal the spinal cord
- spinal cord stimulates Parasympathetic signal to relax the internal sphincter opening the bladder
- the stretch receptor also sends a signal to the cortex of the brain
- cortex voluntarily controls the external sphincter that stays contracted until an appropriate place to relax the muscle and empty the bladder
active transport - energy required
primary: ATP
secondary: energy used from passive transport
endoexcytosis
the effects of ADH on water reabsorption
- released to fix osmolarity problems and increase blood pressure
- reabsorbs water in the last 1/3 distal tubules and collecting ducts to water, causes urine to have high concentration
- absence of ADH kidneys produce dilute urine
aldosterone
- regulates reabsorption of Na+ in the last 1/3 distal tubule s and collecting duct
- aldosterone and ADH always work together
the effects of angiotensin II
- acts on heart to increase blood pressure
- acts on kidney to absorb H2O and salt to increase blood pressure
- acts on hypothalamus to become thirsty and release ADH to reabsorb water
filtration occurs when
hydrostatic pressure in the glomerulus is greater than the osmotic and hydrostatic pressure throughout the entire Bowman’s capsule
filtration only occurs at
Bowman’s capsule
filtration is dependent on
MAP mean arteriole pressure, so if MAP increases GFR increases and vise versa
what is only removed in the descending limb
water
what is only reabsorbed in the ascending limb
Na+, K+, Cl-