anatomy Flashcards
neurotransmitters
the chemical messages past between two neurons at a synapse
action potential
the electrical messages that tells the presynaptic cell to release chemical messages
resting membrane potential
the membrane potential of an unstimulated resting cell
graded membrane potential
a temporary localized change in RMP
Action potential
an electrical impulse that is spread along the surface of an axon occurs when GP is sufficiently large
the resting membrane potential of most neurons is
-70 mv
how does a cell use active forces to maintain resting membrane potential?
sodium-potassium exchange pump where 2K+ goes in the cell and 3Na+ goes out
what would happen if the cell body wasn’t able to maintain resting membrane potential?
no action potential would be generating. No intercellular communication involving nervous system
gated channels (chemically gated)
open when NT bond
gated channels (voltage gated)
open at pre-set
gated channels
stay closed until they get the signal to open (action potential)
during depolarization chemically gated ion channels are
open
what happens during depolarization
Na+ ions enter the cell causing membrane potential to become less negative
the chemical stimulus that was applied to the cell in the first half was an
excitatory neurotransmitter
the chemical stimulus that was applied to the cell in the second half of the graded potential graph was
an inhibitory neurotransmitter
if a graded potential is strong enough for the membrane potential to reach threshold(-55mv) what could occur?
an action potential
look at the graph these are the steps
1: at the resting state theres an sodium/potassium exchange pump: 3 Na+ out/ 2K+ in NO CHANNELS OPEN
2: at the repolarization sodium voltage channels open allowing Na+ to enter cell until K+ channels are closed
3: at the repolarization, potassium channels open allowing K+ to leave. Na+ channels close
4: undershoot refractory period K+ channels close. Na+ channels closed
resting potential
the K+ is in the cell and the Na+ is around it making a -70mV
refractory period
the Na+ is in the cell and the K+ is outside the cell making it -90mV
what determines the action potential speed?
- diameter of the axon
-myelination of axon
excitatory neurotransmitters
acetylcholine
norepinepherine
glutamate
dopamine
inhibitory neurotransmitters
serotonin
GABA
dopamine
steps of intercellular communication pt.1
- a sensory receptor is depolarized by an arriving enviornmental stimulus
- an action potential is generated by the sensory neuron
- the action potential of the sensory neuron arrives at the sensory neurons axon terminal
- the depolarization of the sensory neurons axon terminal opens calcium channels
- an excitatory neurotransmitter is released from the axon terminal of the sensory neuron
- the excitatory neurotransmitter binds to the post synaptic membrane of the interneuron
- chemically gated sodium channels open the interneurons dendrites
steps of intercellular communication pt.2
- a graded potential change occurs on the interneuron
- summation occurs at the axon hillock of the interneuron
- voltage-gated sodium channels open at the axon hillock of the interneuron
- an action potential is generated and spreads down the axon of the interneuron
- the membrane potential pf the interneurons axon reaches +30mV
- potassium channels open on the interneuron
- the sodium-potassium exchange pump restores resting membrane potential