Anaemia Guided Study - IMPORTANT Flashcards
What must the level of haemoglobin be less than in order to be classed as anaemia (in males and females respectively)?
Males:
What are the normal ranges of RBC count in males and females respectively?
Males: 4.6-5.7x10^12/l
Females: 5.0-5.2x10^12/l
What are the normal ranges of haematocrit (Hct) in males and females respectively?
Males: 40-52%
Females: 36-48%
Other than low haemoglobin, low RBC count or low Hct percentage, what can also be a cause of anaemia (perhaps in the more spurious or relative sense)?
Haemodilution - too much plasma
What is the haematocrit (Hct)?
The ratio of volume of RBCs to the total blood volume
What is another, identical way to express haematocrit?
Packed Cell Volume (PCV)
List some symptoms of anaemia.
Tiredness & fatigue Headaches Weakness Light headedness/dizziness Fainting Breathlessness on exertion Palpitations Worsening ischaemic symptoms Menstrual disturbance
List some non-specific signs of anaemia.
Pallor Pale conjunctiva Pale palmar creases Tachycardia Postural hypotension Signs of congestive heart failure (e.g. ankle swelling) Murmur
List some signs specific to iron deficiency anaemia.
Brittle nails & koilonychia
Brittle hair
Angular stomasis
Glossitis
List some signs specific to vitamin B12 anaemia.
Angular stomasis
Glossitis
Jaundice is a tell-tale sign of what type of anaemia?
Haemolytic
Leg ulcers are common in what type of anaemia?
Sickle cell disease based anaemia
A patient is presented with bone deformities - what type of anaemia base is most probable?
Thalassaemia major based anaemia
What happens to RBCs in haemolytic anaemia and what is the result of this?
Destruction of RBCs is higher than the normal rate resulting in increased circulating unconjugated bilirubin (causes yellow pigment seen in jaundice)
What level does bilirubin need to rise above in order to prom the onset of clinical jaundice?
30-50um