Ana

Question 1

Principle of anti nuclear antibodies

Answer 1

Enzyme linked immunosorbent assay
Chemiluminescence immunoassay

Question 2

are assays that can test from a broad range of
antibodies if multiple nuclear antigens are coated onto a single test
well,

Answer 2

Elisa and clia

Question 3

Reagent used in qualitative

Answer 3

Sle latex reagent

Question 4

Positive Result of ana

Answer 4

Agglutination

Question 5

Negative result of ana

Answer 5

No agglutination

Question 6

POSITIVE sera
must show distinct agglutination within

Answer 6

3 mins

Question 7

Agglutination indicates the level of antinuclear antibody
(especially

Answer 7

Anti DNP

Question 8

recommended that the IIF
test remains the gold standard for ANA testing

Answer 8

American College of Rheumatology

Question 9

Acr recommended that the _____remains the gold standard for ANA testing

Answer 9

Indirect immunofluorescent

Question 10

is a chronic systemic inflammatory
disease that affects people usually at the peak age between 20 and 40
years

Answer 10

Systemic lupus erythematosus

Question 11

Systemic Lupus Erythematosus is a chronic systemic inflammatory
disease that affects people usually at the peak age between

Answer 11

20 and 40 years

Question 12

Women are much likely more to be affected than men by a ratio of

Answer 12

9:1

Question 13

This autoimmune disease appears to originate from complex interaction
between several factors, such as

Answer 13

Environmental, genetic and abnormalities in immune system

Question 14

associated with SLE have
been discovered.

Answer 14

100 autoantibodies

Question 15

These include antibodies to double stranded DNA (dsDNA),
histones, and other nuclear components, as well as

Answer 15

Lymphocyte
Erythrocytes
Platelets
Phospholipids
Endothelium
Ribosomal component

Question 16

Laboratory diagnosis of SLE include

Answer 16

Complete blood count
Platelet count
Urinalysis

Question 17

Findings in lupus patients are

Answer 17

Leukopenia, anemia, thrombocytopenia

Question 18

Test may be elevated result of sle

Answer 18

Erythrocyte sedimentation rate

Question 19

Test tends to be low
or normal. Sle result

Answer 19

C reactive protein

Question 20

the first test typically done is a screening test for sle

Answer 20

Anti nuclear antibody

Question 21

They can also be found in some individuals with other conditions, including

Answer 21

chronic infections, pregnancy, and cancer

Question 22

Possible result for IIF TESTING

Answer 22

Speckle
Homogenous
Rim
Nucleolar
Centromere

Question 23

CREST MEANS

Answer 23

Calcinosis
Raynaud phenomenon
Esophageal dysfunction
Sclerodactyly
Telanglectasias

Question 24

calcium deposits in the skin

Answer 24

Calcinosis

Question 25

spasm of blood vessels in response to cold or stress

Answer 25

Raynaud’s phenomenon

Question 26

acid reflux and decrease in motility of esophagus

Answer 26

Esophageal dysfunction

Question 27

thickening and tightening of the skin on the fingers and hands

Answer 27

Sclerodactyly

Question 28

dilation of capillaries causing red marks on surface of skin

Answer 28

Telanglectasias